Recombinant construct P{UAS-abd-A.M}

General Information
Symbol	P{UAS-abd-A.M}	FlyBase ID	FBtp0000738
Feature type	transgenic_transposon

Size		Expression data
Associated insertions	1 available
Molecular map
Recent Updates
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FB2013_03
FB2013_02
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Description & Uses
Species	synthetic construct
Location-dependent role
Description	CV term Qualifiers & info Reference transposon P-element (Michelson, 1994)
Uses	CV term Qualifiers & info Reference binary system (targeted) abd-A (Michelson, 1994) characterization abd-A (Michelson, 1994)
Cloning Sites	Location Restriction sites Reference
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Extent
Segments & Size
Total Size
Left end
Right end

Segments	Number Orientation Symbol
Reference
Features
	CV term Qualifiers & info Reference binary component (Michelson, 1994) chimeric gene (Michelson, 1994) selectable marker (Michelson, 1994)
Component Alleles
Allele	abd-A^{1dB5.Scer\UAS}
Reference(s)	(Azpiazu and Morata, 1998, Bello et al., 2003, Brodu et al., 2002, Foronda et al., 2006, Yao et al., 1999, Alexandre and Vincent, 2003, Lovato et al., 2002, Michelson, 1994, Morata and Sanchez-Herrero, 1999, Bilder and Scott, 1998, Bilder et al., 1998, Casares et al., 1996, de Navas et al., 2006, Hueber et al., 2007, Bello et al., 2007, Enriquez et al., 2010, Maurange et al., 2008, LaBeau et al., 2009)
Molecular data	Construct: abd-A cDNA expressed under influence of UAS regulatory sequences. (Michelson, 1994)
Phenotypic class	increased cell death, with Scer\GAL4^elav-C155 (Maurange et al., 2008) visible, with Scer\GAL4^dpp.blk1 (Yao et al., 1999)
Phenotype manifest in	A1-7 ventral acute muscle 1 \| ectopic \| precursor, with Scer\GAL4^how-24B (Michelson, 1994) A1-7 ventral oblique muscle 6 \| ectopic, with Scer\GAL4^how-24B (Michelson, 1994) A2-7 ventral transverse muscle 1 \| ectopic, with Scer\GAL4^how-24B (Michelson, 1994) abdominal segment 1, with Scer\GAL4^C-765, Scer\GAL4^c739 (Casares et al., 1996) abdominal segment \| ectopic, with Scer\GAL4^C-765, Scer\GAL4^pnr-MD237 (Casares et al., 1996) abdominal segment \| ectopic \| posterior, with Scer\GAL4^C-765, Scer\GAL4^pnr-MD237 (Casares et al., 1996) antenna, with Scer\GAL4^dpp.blk1 (Yao et al., 1999) antenna, with Scer\GAL4^upd-E132 (Casares et al., 1996) aorta primordium, with Scer\GAL4^how-24B (Lovato et al., 2002) aorta primordium, with Scer\GAL4^twi.PG (Lovato et al., 2002) dorsal acute muscle \| ectopic, with Scer\GAL4^how-24B (Enriquez et al., 2010) dorsal closure embryo, with Scer\GAL4^69B (Lovato et al., 2002) embryonic/larval oenocyte \| ectopic, with Scer\GAL4^ato.3.6 (Brodu et al., 2002) embryonic/larval oenocyte \| ectopic, with Scer\GAL4^en-e16E (Brodu et al., 2002) embryonic/larval ostia \| ectopic, with Scer\GAL4^twi.PG (Lovato et al., 2002) embryonic abdominal segment 1 & somatic muscle, with Scer\GAL4^how-24B (Michelson, 1994) embryonic dorsal vessel, with Scer\GAL4^69B (Lovato et al., 2002) embryonic dorsal vessel, with Scer\GAL4^how-24B (Lovato et al., 2002) embryonic dorsal vessel, with Scer\GAL4^twi.PG (Lovato et al., 2002) embryonic mesothoracic segment, with Scer\GAL4^ato.3.6 (Brodu et al., 2002) embryonic mesothoracic segment, with Scer\GAL4^en-e16E (Brodu et al., 2002) embryonic metathoracic segment, with Scer\GAL4^ato.3.6 (Brodu et al., 2002) embryonic metathoracic segment, with Scer\GAL4^en-e16E (Brodu et al., 2002) embryonic prothoracic segment, with Scer\GAL4^ato.3.6 (Brodu et al., 2002) embryonic prothoracic segment, with Scer\GAL4^en-e16E (Brodu et al., 2002) embryonic thoracic segment & somatic muscle, with Scer\GAL4^how-24B (Michelson, 1994) embryonic visceral muscle \| supernumerary, with Scer\GAL4^how-24B (LaBeau et al., 2009) heart primordium, with Scer\GAL4^how-24B (Lovato et al., 2002) heart primordium, with Scer\GAL4^twi.PG (Lovato et al., 2002) leg \| ectopic, with Scer\GAL4^upd-E132 (Casares et al., 1996) metathoracic laterotergite, with Scer\GAL4^C-765, Scer\GAL4^pnr-MD237 (Casares et al., 1996) neuroblast, with Scer\GAL4^elav-C155 (Maurange et al., 2008) neuroblast \| somatic clone, with Scer\GAL4^αTub84B.PL (Bello et al., 2007) scutum, with Scer\GAL4^C-765, Scer\GAL4^pnr-MD237 (Casares et al., 1996) thoracic neuroblast \| larval stage, with Scer\GAL4^αTub84B.PL (Bello et al., 2003) thoracic neuroblast \| larval stage, with Scer\GAL4^αTub84B.PL, Scer\GAL4^elav-C155 (Bello et al., 2003) wing, with Scer\GAL4^Bx-MS1096, Scer\GAL4^C-765 (Casares et al., 1996)
Other information

Allele	w^+mC
Reference(s)	(Michelson, 1994)
Molecular data	Minigene of the white cDNA. (Chung et al., 1993) 4.15kb SpeI fragment of the w gene that carries a deletion of a large part of the first intron and the regulatory region is reduced to 300bp preceding the transcription start site. (Pirrotta, 1988) Construct: A 'mini-white' gene constructed by deletion of the HindIII-XbaI fragment from the long 5' intron. Carried by the Casper series of vectors.
Phenotypic class	courtship behavior defective \| male (Lloyd et al., 2002, Hing and Carlson, 1996) eye color defective (Soldatov et al., 1999, Hagstrom et al., 1996) eye color defective, with Scer\GAL4^Act5C.PI, w^{dsRNA.Sym.Scer\UAS} (Giordano et al., 2002) visible \| dominant (True et al., 1996) visible \| recessive (Roseman et al., 1993)
Phenotype manifest in	pigment cell (Soldatov et al., 1999, Hagstrom et al., 1996, Roseman et al., 1993, Dorer and Henikoff, 1994, Qian and Pirrotta, 1995) pigment cell, with Scer\GAL4^Act5C.PI, w^{dsRNA.Sym.Scer\UAS} (Giordano et al., 2002)
Other information
Expression Data
Reporter Expression

Additional Information
Statement Reference

Marker for
Reflects expression of
Progenitors & Descendants
progenitor(s)	pP{UAS-abd-A.M} (Michelson, 1994)
descendant(s)
Comments

Stocks Listed in FlyBase ( 0 )

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs
Reported As
Symbol Synonym	P{UAS-abd-A.M} (FlyBase, 1996-) UAS-abd-A (Foronda et al., 2006, Lovato et al., 2002, Yao et al., 1999, Michelson, 1994, LaBeau et al., 2009) UAS-Abd-A (Alexandre and Vincent, 2003, Liu et al., 2003, Hueber et al., 2007) UAS-abdA (de Navas et al., 2006, Bello et al., 2007, Enriquez et al., 2010) UAS-AbdA (Maurange et al., 2008) UAS-abdA.M (Brodu et al., 2002)
Secondary FlyBase IDs

References ( 19 )
Research paper	Enriquez et al., 2010, Development 137(3): 457--466 Multi-step control of muscle diversity by Hox proteins in the Drosophila embryo. [FBrf0209729] LaBeau et al., 2009, Mech. Dev. 126(5-6): 478--486 Bithorax Complex genes control alary muscle patterning along the cardiac tube of Drosophila. [FBrf0208061] Maurange et al., 2008, Cell 133(5): 891--902 Temporal transcription factors and their targets schedule the end of neural proliferation in Drosophila. [FBrf0204899] Bello et al., 2007, Development 134(6): 1091--1099 Polycomb group genes are required for neural stem cell survival in postembryonic neurogenesis of Drosophila. [FBrf0202325] Hueber et al., 2007, Development 134(2): 381--392 Comparative analysis of Hox downstream genes in Drosophila. [FBrf0193798] de Navas et al., 2006, Mech. Dev. 123(11): 860--867 A simple and efficient method to identify replacements of P-lacZ by P-Gal4 lines allows obtaining Gal4 insertions in the bithorax complex of Drosophila. [FBrf0194816] Foronda et al., 2006, Development 133(1): 117--127 Requirement of abdominal-A and Abdominal-B in the developing genitalia of Drosophila breaks the posterior downregulation rule. [FBrf0190286] Alexandre and Vincent, 2003, Development 130(4): 729--739 Requirements for transcriptional repression and activation by Engrailed in Drosophila embryos. [FBrf0155721] Bello et al., 2003, Neuron 37(2): 209--219 A pulse of the Drosophila Hox protein Abdominal-A schedules the end of neural proliferation via neuroblast apoptosis. [FBrf0156017] Liu et al., 2003, Development 130(4): 719--728 Drosophila MBF1 is a co-activator for Tracheae Defective and contributes to the formation of tracheal and nervous systems. [FBrf0155720] Brodu et al., 2002, Development 129(12): 2957--2963 abdominal A specifies one cell type in Drosophila by regulating one principal target gene. [FBrf0148967] Lovato et al., 2002, Development 129(21): 5019--5027 The Hox gene abdominal-A specifies heart cell fate in the Drosophila dorsal vessel. [FBrf0151932] Yao et al., 1999, Dev. Biol. 211(2): 268--276 A common mechanism for antenna-to-leg transformation in Drosophila: suppression of homothorax transcription by four HOM-C genes. [FBrf0111139] Azpiazu and Morata, 1998, Genes Dev. 12(2): 261--273 Functional and regulatory interactions between hox and extradenticle genes. [FBrf0099948] Bilder and Scott, 1998, Dev. Biol. 201(1): 43--56 Hedgehog and wingless induce metameric pattern in the Drosophila visceral mesoderm. [FBrf0104409] Bilder et al., 1998, Development 125(9): 1781--1790 Wnt and TGFbeta signals subdivide the AbdA Hox domain during Drosophila mesoderm patterning. [FBrf0102636] Casares et al., 1996, EMBO J. 15(15): 3934--3942 Functional similarity in appendage specification by the Ultrabithorax and abdominal-A Drosophila HOX genes. [FBrf0089610] Michelson, 1994, Development 120(4): 755--768 Muscle pattern diversification in Drosophila is determined by the autonomous function of homeotic genes in the embryonic mesoderm. [FBrf0073912]
Review	Morata and Sanchez-Herrero, 1999, Development 126(13): 2823--2828 Patterning mechanisms in the body trunk and the appendages of Drosophila. [FBrf0108954]