FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term immune system process ID (Ontology) GO:0002376 (Gene Ontology)
Definition Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats.
Comment
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  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS       8
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Genes
 immune system process (all annotations which use CV term, excluding "NOT" statements)       8
     involved_in | immune system process       8
Spanning Tree (Parents/Children)
Only view relationship:
  biological_process
   |__immune system process  614 rec.
       |__activation of immune response 104 rec.
       |   |__activation of innate immune response(+) 103 rec.
       |   |__complement activation(+)
       |   |__immune response-activating signaling pathway(+) 101 rec.
       |__antigen processing and presentation 1 rec.
       |   |__antigen processing and presentation following phagocytosis
       |   |__antigen processing and presentation following pinocytosis(+)
       |   |__antigen processing and presentation initiated by receptor mediated uptake of antigen(+)
       |   |__antigen processing and presentation of endogenous antigen(+)
       |   |__antigen processing and presentation of exogenous antigen(+)
       |   |__antigen processing and presentation of peptide antigen(+) 1 rec.
       |   |__antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(+) 1 rec.
       |   |__antigen processing and presentation via MHC class Ib(+)
       |   |__B cell antigen processing and presentation(+)
       |   |__dendritic cell antigen processing and presentation(+)
       |   |__macrophage antigen processing and presentation(+)
       |   |__monocyte antigen processing and presentation(+)
       |   |__non-professional antigen presenting cell antigen processing and presentation(+)
       |   |__regulation of antigen processing and presentation(+)
       |   |__T cell antigen processing and presentation(+)
       |__antigen sampling in mucosal-associated lymphoid tissue
       |   |__antigen sampling by dendritic cells in mucosal-associated lymphoid tissue
       |   |__antigen sampling by M cells in mucosal-associated lymphoid tissue(+)
       |__B cell selection
       |   |__B cell negative selection(+)
       |   |__B cell positive selection(+)
       |   |__central B cell selection(+)
       |   |__peripheral B cell selection(+)
       |__hemocyte differentiation 51 rec.
       |   |__crystal cell differentiation(+) 25 rec.
       |   |__embryonic hemocyte differentiation(+) 3 rec.
       |   |__hemocyte development 7 rec.
       |   |__larval lymph gland hemocyte differentiation(+) 30 rec.
       |   |__plasmatocyte differentiation(+) 13 rec.
       |   |__regulation of hemocyte differentiation(+) 25 rec.
       |__hemocyte proliferation 46 rec.
       |   |__regulation of hemocyte proliferation(+) 40 rec.
       |__immune effector process 124 rec.
       |   |__cell activation involved in immune response(+)
       |   |__complement activation(+)
       |   |__encapsulation of foreign target(+) 41 rec.
       |   |__granuloma formation(+)
       |   |__immune complex clearance(+)
       |   |__immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(+)
       |   |__induced systemic resistance, ethylene mediated signaling pathway
       |   |__induced systemic resistance, jasmonic acid mediated signaling pathway
       |   |__leukocyte degranulation(+)
       |   |__leukocyte mediated immunity(+)
       |   |__leukocyte migration involved in immune response(+)
       |   |__opsonization(+) 1 rec.
       |   |__regulation of immune effector process(+) 85 rec.
       |   |__respiratory burst involved in defense response(+)
       |__immune response 516 rec.
       |   |__adaptive immune response(+)
       |   |__cell activation involved in immune response(+)
       |   |__cytokine production involved in immune response(+) 1 rec.
       |   |__humoral immune response(+) 151 rec.
       |   |__immune response in gut-associated lymphoid tissue(+)
       |   |__immune response involved in response to exogenous dsRNA 3 rec.
       |   |__immune response to tumor cell(+)
       |   |__immunological memory process
       |   |__inflammatory response to antigenic stimulus(+)
       |   |__innate immune response(+) 368 rec.
       |   |__leukocyte migration involved in immune response(+)
       |   |__organ or tissue specific immune response(+) 12 rec.
       |   |__prostaglandin secretion involved in immune response
       |   |__regulation of immune response(+) 249 rec.
       |   |__type 2 immune response(+)
       |__immune system development 53 rec.
       |   |__hematopoietic or lymphoid organ development(+) 53 rec.
       |   |__somatic diversification of immune receptors
       |   |__tolerance induction
       |__immunological memory process
       |   |__adaptive immune memory response(+)
       |   |__immunological memory formation process(+)
       |   |__innate immunity memory response(+)
       |__leukocyte activation 2 rec.
       |   |__leukocyte activation involved in immune response(+)
       |   |__leukocyte activation involved in inflammatory response(+)
       |   |__leukocyte adhesive activation
       |   |__lymphocyte activation(+)
       |   |__myeloid leukocyte activation(+)
       |   |__plasmacytoid dendritic cell activation(+)
       |   |__regulation of leukocyte activation(+)
       |__leukocyte homeostasis
       |   |__basophil homeostasis
       |   |__dendritic cell homeostasis
       |   |__eosinophil homeostasis
       |   |__lymphocyte homeostasis(+)
       |   |__macrophage homeostasis
       |   |__mast cell homeostasis(+)
       |   |__monocyte homeostasis
       |   |__neutrophil homeostasis(+)
       |__leukocyte migration
       |   |__cellular extravasation(+)
       |   |__diapedesis(+)
       |   |__leukocyte chemotaxis(+)
       |   |__leukocyte migration involved in immune response(+)
       |   |__leukocyte migration involved in inflammatory response(+)
       |   |__mononuclear cell migration(+)
       |   |__myeloid leukocyte migration(+)
       |   |__regulation of leukocyte migration(+)
       |__lymphocyte costimulation
       |   |__B cell costimulation
       |   |__T cell costimulation(+)
       |__myeloid cell homeostasis
       |   |__basophil homeostasis
       |   |__eosinophil homeostasis
       |   |__erythrocyte homeostasis(+)
       |   |__macrophage homeostasis
       |   |__mast cell homeostasis(+)
       |   |__monocyte homeostasis
       |   |__neutrophil homeostasis(+)
       |__production of molecular mediator of immune response 86 rec.
       |   |__antimicrobial peptide production(+) 85 rec.
       |   |__cytokine production involved in immune response(+) 1 rec.
       |   |__granulysin production
       |   |__granzyme A production(+)
       |   |__granzyme B production(+)
       |   |__immunoglobulin production(+)
       |   |__perforin production
       |   |__regulation of production of molecular mediator of immune response(+) 84 rec.
       |__regulation of immune system process 303 rec.
       |   |__negative regulation of immune system process(+) 118 rec.
       |   |__positive regulation of immune system process(+) 193 rec.
       |   |__regulation of activated T cell autonomous cell death(+)
       |   |__regulation of activation-induced cell death of T cells(+)
       |   |__regulation of antigen processing and presentation(+)
       |   |__regulation of hemocyte differentiation(+) 25 rec.
       |   |__regulation of hemocyte proliferation(+) 40 rec.
       |   |__regulation of hemopoiesis(+) 12 rec.
       |   |__regulation of immune effector process(+) 85 rec.
       |   |__regulation of immune response(+) 249 rec.
       |   |__regulation of leukocyte activation(+)
       |   |__regulation of leukocyte migration(+)
       |   |__regulation of mast cell apoptotic process(+)
       |   |__regulation of mature B cell apoptotic process(+)
       |   |__regulation of neutrophil apoptotic process(+)
       |   |__regulation of tolerance induction(+)
       |__somatic diversification of immune receptors
       |   |__somatic diversification of DSCAM-based immune receptors
       |   |__somatic diversification of FREP-based immune receptors
       |   |__somatic diversification of immune receptors by N region addition(+)
       |   |__somatic diversification of immune receptors via alternate splicing(+)
       |   |__somatic diversification of immune receptors via gene conversion(+)
       |   |__somatic diversification of immune receptors via germline recombination within a single locus(+)
       |   |__somatic diversification of immune receptors via somatic mutation(+)
       |   |__somatic diversification of immunoglobulins(+)
       |   |__somatic diversification of T cell receptor genes(+)
       |   |__somatic diversification of variable lymphocyte receptors of jawless fish
       |__T cell selection
       |   |__beta selection
       |   |__extrathymic T cell selection(+)
       |   |__negative T cell selection(+)
       |   |__positive T cell selection(+)
       |   |__thymic T cell selection(+)
       |__tolerance induction
           |__B cell tolerance induction(+)
           |__central tolerance induction(+)
           |__lymphocyte anergy(+)
           |__macrophage tolerance induction(+)
           |__natural killer cell tolerance induction(+)
           |__regulation of tolerance induction(+)
           |__T cell tolerance induction(+)
           |__tolerance induction dependent upon immune response(+)
           |__tolerance induction to lipopolysaccharide
           |__tolerance induction to self antigen(+)
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Wikipedia:Immune_system