FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term cytoplasm ID (Ontology) GO:0005737 (Gene Ontology)
Definition The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.[ ISBN:0198547684 ]
Comment
Links to External Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_CELLULAR_COMPONENT    1899
Genes (FBgn)  TRANSCRIPT_SUBCELLULAR_LOCALIZATION_CVTERM       3
Insertions (FBti)  EXPRESSION_STAGE_TISSUE_POSITION      20
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Alleles Gene Groups Genes Insertions Constructs
 cytoplasm (all annotations which use CV term, excluding "NOT" statements)       --      16   2043     20      6
     colocalizes_with | cytoplasm       --       --       4       --       --
     cytoplasm | apical       --       --       1       --       --
     cytoplasm | male limited       1       --       --       --       --
     cytoplasm | oogenesis       2       --       --       --       2
     cytoplasm | third instar larval stage       1       --       --       --       1
     is_active_in | cytoplasm       --       --    1170       --       --
     located_in | cytoplasm       --       --    1072       --       --
Spanning Tree (Parents/Children)
Only view relationship:
cellular_component
 |__cellular anatomical structure_______
cellular anatomical structure           |
 |__intracellular anatomical structure__|
                                        cytoplasm  8164 rec.
                                         |__acetolactate synthase complex
                                         |__acetyl-CoA carboxylase complex
                                         |   |__acetate CoA-transferase complex(+)
                                         |   |__plastid acetyl-CoA carboxylase complex(+)
                                         |__acidocalcisome
                                         |   |__acidocalcisome lumen
                                         |   |__acidocalcisome membrane
                                         |__alkyl hydroperoxide reductase complex
                                         |__alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)
                                         |__anaerobic ribonucleoside-triphosphate reductase complex
                                         |__anammoxosome
                                         |__anthranilate synthase complex
                                         |__apical cytoplasm
                                         |   |__apical recycling endosome
                                         |__Atg1/ULK1 kinase complex 5 rec.
                                         |__Atg12-Atg5-Atg16 complex 4 rec.
                                         |__basolateral cytoplasm
                                         |   |__basolateral recycling endosome
                                         |__calpain complex
                                         |__carbamoyl-phosphate synthase complex
                                         |__cell cortex 251 rec.
                                         |   |__cell cortex region(+) 90 rec.
                                         |   |__cleavage apparatus septin structure(+)
                                         |   |__cortical cytoskeleton(+) 67 rec.
                                         |   |__cortical dynamic polarity patch
                                         |   |__cortical endoplasmic reticulum(+) 1 rec.
                                         |   |__endocytic patch(+) 1 rec.
                                         |   |__exocyst 9 rec.
                                         |   |__nematocyst
                                         |   |__polarisome(+)
                                         |   |__septin complex(+) 9 rec.
                                         |   |__septin ring(+) 5 rec.
                                         |__cell plate
                                         |__contractile muscle fiber 1086 rec.
                                         |   |__muscle myosin complex 1 rec.
                                         |   |__myofibril(+) 1080 rec.
                                         |   |__smooth muscle contractile fiber(+)
                                         |   |__striated muscle dense body 4 rec.
                                         |__crystalloid
                                         |__CUGBP1-eIF2 complex
                                         |__Cvt complex
                                         |__cysteine synthase complex
                                         |__cytoplasmic cyclin-dependent protein kinase holoenzyme complex
                                         |__cytoplasmic exosome (RNase complex) 9 rec.
                                         |   |__bacterial degradosome
                                         |__cytoplasmic microtubule 54 rec.
                                         |   |__astral microtubule(+) 12 rec.
                                         |   |__axonemal microtubule(+) 16 rec.
                                         |   |__cortical microtubule(+) 3 rec.
                                         |   |__cytoplasmic microtubule minus-end
                                         |   |__cytoplasmic microtubule plus-end(+)
                                         |__cytoplasmic microtubule bundle
                                         |__cytoplasmic origin of replication recognition complex
                                         |__cytoplasmic region 242 rec.
                                         |   |__cell cortex region(+) 90 rec.
                                         |   |__plasma membrane bounded cell projection cytoplasm(+) 155 rec.
                                         |__cytoplasmic replication fork
                                         |   |__cytoplasmic replisome(+)
                                         |__cytoplasmic ribonucleoprotein granule 138 rec.
                                         |   |__chromatoid body
                                         |   |__cytoplasmic stress granule 21 rec.
                                         |   |__cytoplasmic U snRNP body 12 rec.
                                         |   |__GW body
                                         |   |__mutator focus
                                         |   |__neuronal ribonucleoprotein granule 14 rec.
                                         |   |__P granule(+) 54 rec.
                                         |   |__P-body(+) 46 rec.
                                         |   |__RNP body
                                         |   |__TIS granule
                                         |   |__Yb body 8 rec.
                                         |   |__Z granule
                                         |__cytoplasmic ubiquitin ligase complex 4 rec.
                                         |   |__cytoplasmic SCF ubiquitin ligase complex
                                         |   |__ER ubiquitin ligase complex(+) 1 rec.
                                         |   |__VCB complex 3 rec.
                                         |__cytoplasmic vesicle 849 rec.
                                         |   |__aleurone grain(+)
                                         |   |__amorphous vesicle
                                         |   |__carotenoid vesicle
                                         |   |__chitosome(+)
                                         |   |__chloroplast vesicle
                                         |   |__ciliary vesicle
                                         |   |__coated vesicle(+) 88 rec.
                                         |   |__contractile vacuole(+)
                                         |   |__Cvt vesicle(+)
                                         |   |__cytoplasmic vesicle lumen(+) 1 rec.
                                         |   |__cytoplasmic vesicle membrane(+) 166 rec.
                                         |   |__endocytic vesicle(+) 69 rec.
                                         |   |__endosome(+) 439 rec.
                                         |   |__esterosome(+)
                                         |   |__fusiform vesicle
                                         |   |__GARP complex 8 rec.
                                         |   |__Golgi-associated vesicle(+) 40 rec.
                                         |   |__granular vesicle(+)
                                         |   |__gut granule(+)
                                         |   |__mitochondrion-derived vesicle
                                         |   |__multivesicular body, internal vesicle(+) 5 rec.
                                         |   |__osmiophilic body
                                         |   |__pericanalicular vesicle
                                         |   |__pigment granule(+) 25 rec.
                                         |   |__plasma membrane light-harvesting complex(+)
                                         |   |__secretory vesicle(+) 274 rec.
                                         |   |__sperm cytoplasmic droplet
                                         |   |__synaptic vesicle protein transport vesicle
                                         |   |__transport vesicle(+) 253 rec.
                                         |__cytosol 1599 rec.
                                         |   |__3-isopropylmalate dehydratase complex
                                         |   |__6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex
                                         |   |__6-phosphofructokinase complex 1 rec.
                                         |   |__alkanesulfonate monooxygenase complex
                                         |   |__apoptosome 3 rec.
                                         |   |__bacterial degradosome
                                         |   |__canonical inflammasome complex(+)
                                         |   |__chaperonin ATPase complex(+)
                                         |   |__chaperonin-containing T-complex 9 rec.
                                         |   |__cytosol pyruvate dehydrogenase (lipoamide) phosphatase complex
                                         |   |__cytosolic aryl hydrocarbon receptor complex
                                         |   |__cytosolic creatine kinase complex
                                         |   |__cytosolic DNA-directed RNA polymerase complex
                                         |   |__cytosolic electron transfer flavoprotein complex
                                         |   |__cytosolic proteasome complex(+)
                                         |   |__cytosolic region(+) 9 rec.
                                         |   |__cytosolic ribosome(+) 204 rec.
                                         |   |__diamine N-acetyltransferase complex
                                         |   |__ER membrane insertion complex(+) 4 rec.
                                         |   |__fatty-acyl-CoA synthase complex
                                         |   |__FMN reductase complex
                                         |   |__FtsBL complex
                                         |   |__geranylgeranyltransferase-III complex
                                         |   |__GLI-SUFU complex
                                         |   |__guanylate cyclase complex, soluble 7 rec.
                                         |   |__H-NS complex
                                         |   |__H-NS-Hha complex
                                         |   |__hemoglobin complex
                                         |   |__IkappaB kinase complex 1 rec.
                                         |   |__intramolecular phosphotransferase complex(+)
                                         |   |__Las1 complex 1 rec.
                                         |   |__mCRD-mediated mRNA stability complex 1 rec.
                                         |   |__ModE complex
                                         |   |__molybdopterin adenylyltransferase complex 2 rec.
                                         |   |__non-canonical inflammasome complex
                                         |   |__phosphopyruvate hydratase complex 1 rec.
                                         |   |__ribonucleoside-diphosphate reductase complex 3 rec.
                                         |   |__ripoptosome
                                         |   |__SsuD-SsuE complex
                                         |   |__steroid hormone aporeceptor complex
                                         |   |__sulfurtransferase complex(+) 11 rec.
                                         |   |__taurine dioxygenase complex
                                         |   |__TSC1-TSC2 complex 4 rec.
                                         |   |__Yae1-Lto1 complex
                                         |__cytosolic translation preinitiation complex 6 rec.
                                         |   |__eukaryotic 43S preinitiation complex 5 rec.
                                         |   |__eukaryotic 48S preinitiation complex 1 rec.
                                         |__dense body
                                         |__dynein axonemal particle 4 rec.
                                         |__electron transfer flavoprotein complex 3 rec.
                                         |   |__cytosolic electron transfer flavoprotein complex
                                         |   |__mitochondrial electron transfer flavoprotein complex 2 rec.
                                         |__endoplasmic reticulum 750 rec.
                                         |   |__endoplasmic reticulum exit site 21 rec.
                                         |   |__endoplasmic reticulum lumen(+) 18 rec.
                                         |   |__endoplasmic reticulum protein-containing complex(+) 88 rec.
                                         |   |__endoplasmic reticulum quality control compartment 1 rec.
                                         |   |__endoplasmic reticulum subcompartment(+) 382 rec.
                                         |   |__membrane stack
                                         |   |__perinuclear endoplasmic reticulum(+) 9 rec.
                                         |   |__plasmodesmatal desmotubule(+)
                                         |   |__plasmodesmatal endoplasmic reticulum
                                         |   |__rough endoplasmic reticulum(+) 31 rec.
                                         |   |__sarcoplasmic reticulum(+) 15 rec.
                                         |   |__smooth endoplasmic reticulum(+) 7 rec.
                                         |__endoplasmic reticulum-Golgi intermediate compartment 25 rec.
                                         |   |__endoplasmic reticulum-Golgi intermediate compartment membrane
                                         |   |__TRAPPI protein complex 1 rec.
                                         |__endosperm protein body 12 rec.
                                         |__eukaryotic translation elongation factor 1 complex 5 rec.
                                         |__eukaryotic translation initiation factor 2 complex 4 rec.
                                         |__eukaryotic translation initiation factor 2B complex 6 rec.
                                         |__eukaryotic translation initiation factor 3 complex 16 rec.
                                         |   |__eukaryotic translation initiation factor 3 complex, eIF3e 1 rec.
                                         |   |__eukaryotic translation initiation factor 3 complex, eIF3m 4 rec.
                                         |__eukaryotic translation initiation factor 4F complex 12 rec.
                                         |__FHF complex
                                         |__fusome 93 rec.
                                         |__G-protein beta/gamma-Btk complex
                                         |__G-protein beta/gamma-Raf-1 complex
                                         |__G-protein beta/gamma-subunit complex
                                         |__glutamate-cysteine ligase complex 3 rec.
                                         |__glutamate-tRNA ligase complex
                                         |__glycerol-3-phosphate dehydrogenase (FAD) complex
                                         |__glycine reductase complex
                                         |__glycine-tRNA ligase complex
                                         |__glycogen granule 5 rec.
                                         |__glycolate oxidase complex
                                         |__goblet cell theca
                                         |__Golgi apparatus 512 rec.
                                         |   |__acroblast 15 rec.
                                         |   |__cis-Golgi network(+) 19 rec.
                                         |   |__clathrin coat of trans-Golgi network vesicle(+) 11 rec.
                                         |   |__COPI vesicle coat 9 rec.
                                         |   |__exomer complex
                                         |   |__GARP complex 8 rec.
                                         |   |__Golgi apparatus subcompartment(+) 140 rec.
                                         |   |__Golgi lumen(+)
                                         |   |__Golgi membrane(+) 121 rec.
                                         |   |__Golgi transport complex 9 rec.
                                         |   |__Golgi-associated vesicle lumen
                                         |   |__inositol phosphoceramide synthase complex
                                         |   |__postsynaptic Golgi apparatus 4 rec.
                                         |   |__Ric1-Rgp1 guanyl-nucleotide exchange factor complex 2 rec.
                                         |   |__TRAPPII protein complex 10 rec.
                                         |   |__TRAPPIII protein complex 12 rec.
                                         |__histone mRNA stem-loop binding complex
                                         |__homodimeric polyprenyl diphosphate synthase complex
                                         |__homomeric SMAD protein complex
                                         |__HSP90-CDC37 chaperone complex
                                         |__hydrogenosome
                                         |   |__hydrogenosomal membrane
                                         |   |__hydrogenosome lumen
                                         |__hydroxyisourate hydrolase complex
                                         |__imidazoleglycerol-phosphate synthase complex
                                         |__iron-sulfur cluster assembly complex 17 rec.
                                         |   |__cytosolic [4Fe-4S] assembly scaffold complex 3 rec.
                                         |   |__cytosolic [4Fe-4S] assembly targeting complex 5 rec.
                                         |   |__IscS-IscU complex
                                         |   |__mitochondrial [2Fe-2S] assembly complex 6 rec.
                                         |   |__mitochondrial [4Fe-4S] assembly complex 3 rec.
                                         |__keratohyalin granule
                                         |__membrane coat 41 rec.
                                         |   |__AP-type membrane coat adaptor complex(+) 18 rec.
                                         |   |__clathrin coat(+) 20 rec.
                                         |   |__vesicle coat(+) 35 rec.
                                         |__methane-oxidizing organelle
                                         |__methionyl glutamyl tRNA synthetase complex
                                         |__methylosome 1 rec.
                                         |__microbody 114 rec.
                                         |   |__microbody lumen(+) 3 rec.
                                         |   |__microbody membrane(+) 29 rec.
                                         |   |__peroxisome(+) 114 rec.
                                         |   |__Woronin body
                                         |__mitochondrial cloud
                                         |__mitochondrion 1669 rec.
                                         |   |__kinetoplast(+)
                                         |   |__mitochondrial envelope(+) 614 rec.
                                         |   |__mitochondrial intracristal space
                                         |   |__mitochondrial matrix(+) 379 rec.
                                         |   |__mitochondrial protein-containing complex(+) 224 rec.
                                         |__mitosome
                                         |__mitotic spindle assembly checkpoint MAD1-MAD2 complex
                                         |__monolayer-surrounded lipid storage body outer lipid monolayer
                                         |__multi-eIF complex 4 rec.
                                         |__Myo2p-Vac17p-Vac8p transport complex
                                         |__N-terminal protein acetyltransferase complex 16 rec.
                                         |   |__NatA complex 4 rec.
                                         |   |__NatB complex 5 rec.
                                         |   |__NatC complex 6 rec.
                                         |__nascent polypeptide-associated complex 12 rec.
                                         |__neurofilament
                                         |__ooplasm 4 rec.
                                         |   |__cytoplasmic lattice
                                         |__PAN complex 2 rec.
                                         |__Par3-APC-KIF3A complex
                                         |__paraferritin complex
                                         |__perinuclear region of cytoplasm 96 rec.
                                         |   |__cytoplasmic periphery of the nuclear pore complex
                                         |   |__mutator focus
                                         |   |__perinuclear endoplasmic reticulum(+) 9 rec.
                                         |   |__perinuclear theca(+)
                                         |__periphagosomal region of cytoplasm
                                         |__phagophore 2 rec.
                                         |__phagophore assembly site 21 rec.
                                         |   |__phagophore assembly site membrane(+) 10 rec.
                                         |__phenylalanine-tRNA ligase complex 2 rec.
                                         |__phosphoenolpyruvate-dependent sugar phosphotransferase complex
                                         |__phosphopantothenoylcysteine decarboxylase complex 1 rec.
                                         |__phosphoribosylaminoimidazole carboxylase complex
                                         |__phosphorylase kinase complex 3 rec.
                                         |__phragmoplast
                                         |__phragmosome
                                         |__pICln-Sm protein complex 5 rec.
                                         |__pirellulosome
                                         |__plasma membrane-derived chromatophore
                                         |   |__chromatophore ribulose bisphosphate carboxylase complex(+)
                                         |   |__plasma membrane light-harvesting complex(+)
                                         |   |__plasma membrane-derived chromatophore membrane(+)
                                         |   |__xanthophore
                                         |__plasma membrane-derived photosystem I
                                         |__plasma membrane-derived thylakoid photosystem II
                                         |__plastid
                                         |   |__amyloplast(+)
                                         |   |__apicoplast(+)
                                         |   |__chloroplast(+)
                                         |   |__chromoplast(+)
                                         |   |__cyanelle(+)
                                         |   |__etioplast(+)
                                         |   |__gerontoplast(+)
                                         |   |__leucoplast(+)
                                         |   |__nucleomorph
                                         |   |__phenyloplast
                                         |   |__plastid ADPG pyrophosphorylase complex(+)
                                         |   |__plastid envelope(+)
                                         |   |__plastid mRNA editing complex
                                         |   |__plastid stroma(+)
                                         |   |__plastid thylakoid(+)
                                         |   |__plastid-encoded plastid RNA polymerase complex(+)
                                         |   |__proplastid(+)
                                         |   |__pyrenoid(+)
                                         |   |__starch grain(+)
                                         |__pole plasm 150 rec.
                                         |   |__germ plasm(+) 58 rec.
                                         |__polkadots
                                         |__polyhydroxyalkanoate granule
                                         |__polyketide synthase complex
                                         |   |__type II polyketide synthase complex
                                         |   |__type III polyketide synthase complex
                                         |__preprophase band
                                         |__procentriole
                                         |__procentriole replication complex
                                         |__proteasome storage granule 2 rec.
                                         |__protein farnesyltransferase complex 2 rec.
                                         |__protein phosphatase type 1 complex 13 rec.
                                         |   |__PTW/PP1 phosphatase complex 6 rec.
                                         |__pyruvate dehydrogenase (lipoamide) phosphatase complex 2 rec.
                                         |   |__cytosol pyruvate dehydrogenase (lipoamide) phosphatase complex
                                         |   |__mitochondrial pyruvate dehydrogenase (lipoamide) phosphatase complex 2 rec.
                                         |__Rab-protein geranylgeranyltransferase complex 4 rec.
                                         |__RasGAP-Fyn-Lyn-Yes complex
                                         |__RAVE complex 2 rec.
                                         |__ribulose bisphosphate carboxylase complex
                                         |   |__chloroplast ribulose bisphosphate carboxylase complex
                                         |   |__chromatophore ribulose bisphosphate carboxylase complex(+)
                                         |__sarcoplasm 18 rec.
                                         |   |__junctional membrane complex 1 rec.
                                         |   |__sarcoplasmic reticulum(+) 15 rec.
                                         |__sarcosine oxidase complex
                                         |__SCAR complex 6 rec.
                                         |__scintillon
                                         |__Scrib-APC complex
                                         |__Scrib-APC-beta-catenin complex
                                         |__serine-pyruvate aminotransferase complex
                                         |__Sid2-Mob1 complex
                                         |__signal recognition particle 9 rec.
                                         |   |__signal recognition particle, chloroplast targeting
                                         |   |__signal recognition particle, endoplasmic reticulum targeting 9 rec.
                                         |   |__signal recognition particle, plasma membrane targeting
                                         |__Ski complex 3 rec.
                                         |__SMN-Sm protein complex 16 rec.
                                         |   |__Lsm-containing SMN-Sm protein complex 1 rec.
                                         |   |__SmD-containing SMN-Sm protein complex 2 rec.
                                         |   |__SMN complex 12 rec.
                                         |__SNARE complex 36 rec.
                                         |   |__cellubrevin-VAMP4-endobrevin-syntaxin-6 complex
                                         |   |__cellubrevin-VAMP4-syntaxin-16 complex
                                         |   |__endobrevin-SNAP-25-syntaxin-1a complex
                                         |   |__endobrevin-SNAP-25-syntaxin-2 complex
                                         |   |__endobrevin-synaptobrevin 2-alpha-SNAP-NSF-syntaxin-4 complex
                                         |   |__platelet SNARE complex
                                         |   |__synaptobrevin 2-SNAP-25-syntaxin-1a complex
                                         |   |__synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex
                                         |   |__synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex
                                         |   |__synaptobrevin 2-SNAP-25-syntaxin-2 complex
                                         |   |__synaptobrevin 2-SNAP-25-syntaxin-3 complex
                                         |   |__synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex
                                         |   |__synaptobrevin 2-SNAP-25-syntaxin-4 complex
                                         |   |__synaptotagmin-synaptobrevin 2-SNAP-25-syntaxin-1a-syntaxin-1b-Rab3a complex
                                         |   |__synaptotagmin-synaptobrevin 2-SNAP-25-syntaxin-1a-syntaxin-1b-Rab3a-complexin II complex
                                         |   |__synaptotagmin-synaptobrevin 2-SNAP-25-syntaxin-1a-syntaxin-1b-Unc13 complex
                                         |   |__syntaxin-6-syntaxin-16-Vti1a complex
                                         |   |__VAMP4-syntaxin-6-syntaxin-16-Vti1a complex
                                         |__spectrosome 77 rec.
                                         |__subsynaptic reticulum 37 rec.
                                         |__sulfate adenylyltransferase complex (ATP)
                                         |__translation initiation complex
                                         |   |__eukaryotic 80S initiation complex
                                         |   |__mitochondrial translation initiation complex
                                         |__translation initiation ternary complex
                                         |__translation release factor complex 3 rec.
                                         |__transnitrosylase complex
                                         |   |__iNOS-S100A8/A9 complex
                                         |__tricarboxylic acid cycle heteromeric enzyme complex 21 rec.
                                         |   |__isocitrate dehydrogenase complex (NAD+) 6 rec.
                                         |   |__oxoglutarate dehydrogenase complex 8 rec.
                                         |   |__succinate-CoA ligase complex(+) 7 rec.
                                         |__type I site-specific deoxyribonuclease complex
                                         |__type II site-specific deoxyribonuclease complex
                                         |__type III site-specific deoxyribonuclease complex
                                         |__type IV site-specific deoxyribonuclease complex
                                         |__UFD1-NPL4 complex
                                         |__urease complex
                                         |__vacuole 378 rec.
                                         |   |__acrosomal matrix
                                         |   |__autophagosome(+) 128 rec.
                                         |   |__contractile vacuole(+)
                                         |   |__lytic vacuole(+) 216 rec.
                                         |   |__micropexophagy-specific membrane apparatus
                                         |   |__plant-type vacuole(+)
                                         |   |__post-lysosomal vacuole
                                         |   |__storage vacuole(+)
                                         |   |__vacuolar lumen(+) 2 rec.
                                         |   |__vacuolar membrane(+) 103 rec.
                                         |__VCP-NSFL1C complex
                                         |__WASH complex 8 rec.
                                         |__yolk 118 rec.
                                             |__yolk granule 50 rec.
                                             |__yolk plasma 9 rec.
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Is a cellular anatomical structure
Part of intracellular anatomical structure
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Wikipedia:Cytoplasm