FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term innate immune response ID (Ontology) GO:0045087 (Gene Ontology)
Definition Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens.
Also Known As "innate immunity" ; "nonspecific immune response"
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Links to External Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
    Results list data from multiple species. Click on a button above and use the 'Filter by species' options on the resulting HitList to retrieve species-specific data.
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS     147
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 innate immune response (all annotations which use CV term, excluding "NOT" statements)       4    147
     acts_upstream_of | innate immune response       --       1
     involved_in | innate immune response       --     146
Spanning Tree (Parents/Children)
Only view relationship:
immune system process
 |__immune response_________________
response to stimulus                |
 |__immune response_________________|
defense response to other organism  |
 |__defense response to symbiont____|
                                    innate immune response  368 rec.
                                     |__age-related resistance
                                     |   |__regulation of age-related resistance(+)
                                     |__antibacterial innate immune response 2 rec.
                                     |__antifungal innate immune response 13 rec.
                                     |   |__regulation of antifungal innate immune response(+) 2 rec.
                                     |__antiviral innate immune response 5 rec.
                                     |__complement activation, alternative pathway
                                     |   |__regulation of complement activation, alternative pathway(+)
                                     |__complement activation, GZMK pathway
                                     |__complement activation, lectin pathway
                                     |   |__regulation of complement activation, lectin pathway(+)
                                     |__hemolymph coagulation 8 rec.
                                     |__host-mediated suppression of symbiont invasion 4 rec.
                                     |__induced systemic resistance
                                     |   |__induced systemic resistance, ethylene mediated signaling pathway
                                     |   |__induced systemic resistance, jasmonic acid mediated signaling pathway
                                     |__innate immune response in mucosa
                                     |__innate immunity memory response
                                     |   |__regulation of innate immunity memory response(+)
                                     |__melanization defense response 58 rec.
                                     |   |__melanotic encapsulation of foreign target(+) 32 rec.
                                     |   |__regulation of melanization defense response(+) 13 rec.
                                     |__natural killer cell activation involved in immune response
                                     |   |__natural killer cell degranulation(+)
                                     |__natural killer cell mediated immunity
                                     |   |__natural killer cell cytokine production(+)
                                     |   |__natural killer cell mediated cytotoxicity(+)
                                     |   |__natural killer cell mediated immune response to tumor cell(+)
                                     |   |__regulation of natural killer cell mediated immunity(+)
                                     |__plant-type hypersensitive response
                                     |   |__regulation of plant-type hypersensitive response(+)
                                     |__regulation of innate immune response 177 rec.
                                     |   |__negative regulation of innate immune response(+) 39 rec.
                                     |   |__positive regulation of innate immune response(+) 138 rec.
                                     |   |__regulation of age-related resistance(+)
                                     |   |__regulation of antifungal innate immune response(+) 2 rec.
                                     |   |__regulation of complement activation, alternative pathway(+)
                                     |   |__regulation of complement activation, lectin pathway(+)
                                     |   |__regulation of innate immunity memory response(+)
                                     |   |__regulation of melanization defense response(+) 13 rec.
                                     |   |__regulation of natural killer cell mediated immunity(+)
                                     |   |__regulation of pattern recognition receptor signaling pathway(+) 69 rec.
                                     |   |__regulation of plant-type hypersensitive response(+)
                                     |   |__regulation of respiratory burst involved in inflammatory response(+)
                                     |   |__regulation of response to type II interferon(+)
                                     |   |__regulation of type I interferon-mediated signaling pathway(+)
                                     |__response to type I interferon
                                     |   |__cellular response to type I interferon(+)
                                     |__response to type II interferon
                                     |   |__cellular response to type II interferon(+)
                                     |   |__regulation of response to type II interferon(+)
                                     |__response to type III interferon
                                     |   |__cellular response to type III interferon(+)
                                     |__RNAi-mediated antiviral immune response 5 rec.
                                         |__RNAi-mediated antiviral immunity against DNA virus
                                         |__RNAi-mediated antiviral immunity against RNA virus 2 rec.
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Is a immune response
defense response to symbiont
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Synonyms
  • "innate immunity" EXACT
    "nonspecific immune response" EXACT
Secondary IDs
hide External Crossreferences & Linkouts
Reactome:R-HSA-168249 "Innate Immune System"
Wikipedia:Innate_immune_system