FB2026_02 , released June 18, 2026
Aberration: Dmel\Df(2L)E66
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General Information
Symbol
Df(2L)E66
Species
D. melanogaster
Name
Deficiency (2L) Enhancer of variegation
FlyBase ID
FBab0001459
Feature type
chromosomal_deletion
Also Known As
E66, E(var)66
Computed Breakpoints include

25F3;26B1

Features within 25F3--26B1
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Mutagen
PM hybrid dysgenesis
(Locke et al., 1988)
Class of aberration (relative to wild type)
chromosomal_deletion
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Barad et al., 1991, Locke et al., 1988)
Breakpoints

25F2-25F3;26A6-26B1

(Locke et al., 1988)

25F3-25F4;26B1-26B2

(Barad et al., 1991)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data

bk1 << E(var)26A << bk2

Genetic mapping information
Comments
Comments on Cytology

Left limit of break 1 from polytene analysis (FBrf0053742) Right limit of break 1 from polytene analysis (FBrf0048198) Left limit of break 2 from polytene analysis (FBrf0053742) Right limit of break 2 from polytene analysis (FBrf0048198)

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
E(var)26A
(Locke et al., 1988)
Partially deleted / disrupted
Molecular Data
Completely deleted
Partially deleted
Genes NOT Deleted / Disrupted
Complementation Data
 
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (0)
    If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
    In these cases, there will be no "Export to Hitlist" button to the left.
    Phenotypic Data
    In combination with other aberrations

    Effect on variegation of y in In(1)y3P and Sb in T(2;3)SbV studied: inactivation of y occurs independently of inactivation of Sb.

    (Bishop, 1992)

    Enhances position-effect variegation of In(1)y3P.

    (Tartof and Bremer, 1990)

    Dominantly enhances position effect variegation at the w locus caused by In(1)wm4, C(1;YL)wmMc or T(1;4)wm5 and position effect variegation at the y locus caused by In(1)y3P. Df(2L)E66 when present with Dp(2;2)AM3, Dp(2;2)AM17, Dp(2;2)AM18, Dp(2;2)AM33, Dp(2;2)AM34 or Dp(2;2)AM37 does not suppress or enhance position effect variegation at the w locus caused by In(1)wm4. Position effect variegation at the w locus is not seen when Df(2L)E66 is combined with In(1)wm4rv5, In(1)wm4rv6 or In(1)wm4rv26.

    (Locke et al., 1988)
    NOT in combination with other aberrations

    Enhance mottling in wm4.

    (Tartof et al., 1989)

    Homozygous lethal.

    (Locke et al., 1988)

    Enhances position-effect variegation of In(1)wm4. Recessive lethal.

    Stocks (0)
    Notes on Origin
    Discoverer
     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     
    Synonyms and Secondary IDs (4)
    Reported As
    Symbol Synonym
    Df(2L)E66
    E(var)66
    (Sabl and Henikoff, 1996, Tartof and Bremer, 1990)
    E66
    (Tartof et al., 1989, Locke et al., 1988)
    Name Synonyms
    Deficiency (2L) Enhancer of variegation
    Secondary FlyBase IDs
      References (8)