FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Aberration: Dmel\Df(2R)Egfr3
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General Information
Symbol
Df(2R)Egfr3
Species
D. melanogaster
Name
Deficiency (2R) Epidermal growth factor
FlyBase ID
FBab0001959
Feature type
chromosomal_deletion
Also Known As
egfr3F18, flb3F18, DER3F18
Computed Breakpoints include

57E1;57F5-57F10

Features within 57E1--57F10
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Mutagen
ethyl methanesulfonate
Class of aberration (relative to wild type)
chromosomal_deletion
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Clifford and Schupbach, 1989, Price et al., 1989)
Breakpoints

57E1;57F5-57F11

(Price et al., 1989)

57D8-57E1;57F5-57F10

(Clifford and Schupbach, 1989)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data

bk1 << l(2)57Eb << bk2

Genetic mapping information
Comments
Comments on Cytology

Ref: Price et al., 1989, Cell 56: 1085--1092

(Clifford and Schupbach, 1989)

Limits of break 1 from polytene analysis (FBrf0049331) Left limit of break 2 from polytene analysis (FBrf0049331) Right limit of break 2 from polytene analysis (FBrf0049928)

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Genes NOT Deleted / Disrupted
Complementation Data
 
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (0)
    If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
    In these cases, there will be no "Export to Hitlist" button to the left.
    Phenotypic Data
    In combination with other aberrations
    NOT in combination with other aberrations

    Egfrf3/Df(2R)Egfr3 embryos exhibit no ventral cuticle and the anterior has a large hole. No Egfrf3/Df(2R)Egfr3 mutant discs could be in vivo cultured.

    (Simcox, 1997)

    Homozygotes and hemizygotes display a severe 'flb' phenotype.

    (Clifford and Schupbach, 1989)

    Abdominal denticle belts and head skeleton are almost absent. Germ band has not retracted and the cuticle size is much reduced.

    (Price et al., 1989)

    Severe lethal phenotype: anterior structures deteriorate, ventral denticle bands are missing, germ band does not retract and the CNS shows a collapse of commissure and midline pattern.

    (Schejter and Shilo, 1989)
    Stocks (2)
    Notes on Origin
    Discoverer
     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     
    Synonyms and Secondary IDs (13)
    Reported As
    Symbol Synonym
    DER3F18
    (Simcox, 1997, Schnepp et al., 1996)
    Df(2R)Egfr3
    Df(2R)Egfr3F18
    Df(2R)egfr3F18
    (Alvarado et al., 2004)
    Df(2R)top3F18
    (Clifford and Schupbach, 1989)
    Egf-r<up>Df F18</up>
    (Sturtevant et al., 1993)
    Egfr3F18
    (Austin et al., 2014, Butchar et al., 2012, Rawlings et al., 2004)
    EgfrDf
    (Schnorr et al., 2001)
    egfr3F18
    (Alvarado et al., 2004)
    flb3F18
    (Kraut and Campos-Ortega, 1996, Baker and Rubin, 1992, Schejter and Shilo, 1989)
    flb3F
    (O'Keefe et al., 1997)
    top3F18
    (Price et al., 1989)
    Name Synonyms
    Deficiency (2R) Epidermal growth factor
    Secondary FlyBase IDs
      References (18)