FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Aberration: Dmel\In(1)scS1
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General Information
Symbol
In(1)scS1
Species
D. melanogaster
Name
Inversion (1) scute of Sinitskaya
FlyBase ID
FBab0004216
Feature type
chromosomal_inversion
Computed Breakpoints include

1B3-1B4;h32

Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Mutagen
X ray
Class of aberration (relative to wild type)
chromosomal_inversion
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_inversion
(Lindsley and Grell, 1968)
Breakpoints

1B3-1B4;20B-20D1

(Lindsley and Grell, 1968)
Causes alleles
scS1
(Campuzano et al., 1985)
Carries alleles
Transposon Insertions
Formalized genetic data

bk1 hits sc << bb << bk2

Genetic mapping information
Comments

Breakpoint(s) molecularly mapped

(Campuzano et al., 1985, Carramolino et al., 1982)

Breakpoint between DNA coordinates +28.2 and +26.9 (Campuzano et al., 1985). 0 is an arbitrarily chosen EcoRI site in the scĪ² segment of ASC; positive values to the left (Carramolino, Ruiz-Gomez, Guererro, Campuzano and Modolell, 1982, EMBO J. 1: 1185-92).

Comments on Cytology

Cytology inferred from genetic identity of left break with that of In(1)sc4 and right break with that of with In(1)sc8.

(Lindsley and Grell, 1968)

Limits of break 1 from polytene analysis (FBrf0042024) Limits of break 2 from polytene analysis (citation unavailable)

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
sc
(Muller et al., 1937)
Partially deleted / disrupted
Molecular Data
Completely deleted
Partially deleted
Genes NOT Deleted / Disrupted
Complementation Data
 
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (0)
    If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
    In these cases, there will be no "Export to Hitlist" button to the left.
    Phenotypic Data
    In combination with other aberrations
    NOT in combination with other aberrations

    Homozygous females show an almost complete loss of tergite chaetae.

    (Mari-Beffa et al., 1991)

    Homozygous females are sterile.

    (Durica and Krider, 1978)

    Homozygous female sterile (Pucket and Snyder, 1973, Genetics 74: s221). In(1)scS1/0 almost completely male lethal (Baker, 1971; Pucket and Snyder, 1973), the adult survivors extreme scute and almost immotile, with reduction in rRNA (Nix, 1973). In gynandromorphs, however, In(1)scS1/0 cells viable and normal in appearance suggesting that position effect suppression of rRNA is non-autonomous (Pyati, 1976, Genet. Res. 28: 89-91).

    Stocks (3)
    Notes on Origin
    Discoverer

    Sinitskaya, March 1934.

     

    Induced with In(1)S.

    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     
    Synonyms and Secondary IDs (5)
    Reported As
    Symbol Synonym
    In(1)scS1
    In(1)scs1
    (Abramov et al., 2005)
    In(1)scS1
    scS1
    (Mari-Beffa et al., 1991)
    Name Synonyms
    Inversion (1) scute of Sinitskaya
    Secondary FlyBase IDs
      References (26)