FB2026_03 , released September 17, 2026
Aberration: Dmel\In(2R)Adv
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General Information
Symbol
In(2R)Adv
Species
D. melanogaster
Name
FlyBase ID
FBab0004938
Feature type
chromosomal_inversion
Computed Cytological Breakpoints (relative to progenitor)

48B-48C;58D-58E

Sequenced Breakpoints (relative to progenitor)
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Mutagen
X ray
(Preiss and Artavanis-Tsakonas, 1991)
Class of aberration (relative to wild type)
chromosomal_inversion
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_inversion
Cytological Breakpoints (relative to progenitor)

48B-48C;58D-58E

(Preiss and Artavanis-Tsakonas, 1991)
Causes alleles
Adv1
(Srivastava et al., 2002, Preiss and Artavanis-Tsakonas, 1991)
enAdv-1
(Srivastava et al., 2002)
Carries alleles
Transposon Insertions
Formalized genetic data

bk1 << Adv << bk2

Genetic mapping information
Comments
Comments on Cytology

All limits from polytene analysis (FBrf0053664)

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
en
(Srivastava et al., 2002)
Partially deleted / disrupted
Molecular Data
Completely deleted
Partially deleted
Genes NOT Deleted / Disrupted
Complementation Data
 
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (0)
    If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
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    Phenotypic Data
    In combination with other aberrations

    In(2R)Adv is lethal in combination with In(2R)vgW.

    (Srivastava et al., 2002)

    Inferred to overlap with: In(2R)vgW.

    (Srivastava et al., 2002)
    NOT in combination with other aberrations
    Stocks (0)
    Notes on Origin
    Discoverer
     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     

    While complementation data indicate that the recessive lethality of In(2R)Adv is due to disruption of en, en expression appears normal in heterozygotes, suggesting that the dominant "additional vein" phenotype of this inversion is not due to its effects on en. Note - in situ hybridisation of polytene chromosomes with en cDNA also supports disruption of en by one of the breakpoints.

    (Srivastava et al., 2002)
    Synonyms and Secondary IDs (2)
    Reported As
    Symbol Synonym
    Adv
    (Srivastava et al., 2002)
    In(2R)Adv
    Name Synonyms
    Secondary FlyBase IDs
      References (3)