FB2026_03 , released September 17, 2026
Aberration: Dmel\T(1;2;3;4)l-v454
Open Close
General Information
Symbol
T(1;2;3;4)l-v454
Species
D. melanogaster
Name
Translocation (1;2;3;4) lethal-variegated
FlyBase ID
FBab0006230
Feature type
chromosomal_translocation
Computed Cytological Breakpoints (relative to progenitor)

12B;22-3;44F;81;101F

Sequenced Breakpoints (relative to progenitor)
Member of large scale dataset(s)
Nature of Aberration
Cytological Order

1Lt - 12B | 81 - 3Lt ; 2Lt - 22 | 12B - 1Rt ; 2Rt - 44F | 101 - 4Rt ; 3Rt - 81 | 23 - 44F | 101 - 4Rt

(Lindsley et al., 1960)
Progenitor
Mutagen
X ray
(Lindsley et al., 1960)
Class of aberration (relative to wild type)
chromosomal_translocation
Class of aberration (relative to progenitor)
Cytological Breakpoints (relative to progenitor)

12B;22-23;44F;81;101F

(Lindsley et al., 1960)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data

bk1 hits l(1)v454

Genetic mapping information
Comments
Comments on Cytology

All limits from polytene analysis (FBrf0013319)

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
Partially deleted / disrupted
Molecular Data
Completely deleted
Partially deleted
Genes NOT Deleted / Disrupted
Complementation Data
 
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (0)
    If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
    In these cases, there will be no "Export to Hitlist" button to the left.
    Phenotypic Data
    In combination with other aberrations
    NOT in combination with other aberrations

    X/0 males are lethal (relative viability of 0), X/Y males have reduced viability (relative viability of 0.5). Levels of maternal nondisjunction are high. Males are sterile. Recovery of male lethals is reduced when in combination with either E(var)71 or Df(2R)M41A10 : the Y-suppressed lethality is a variegated position effect.

    (Lindsley et al., 1960)

    Male sterile failure of sperm head elongation viability XY: .50 X0 male lethal XY male sterile Enhanced by Df(2R)M41A10 Enhanced by Evar7

    Stocks (0)
    Notes on Origin
    Discoverer

    Lindsley, Edington and Von Halle.

     

    Selected as X chromosomes lethal or semilethal in X0 males, but viable in XY males.

    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     
    Synonyms and Secondary IDs (3)
    Reported As
    Symbol Synonym
    T(1;2;3;4)l-v454
    l(1)v454
    Name Synonyms
    Translocation (1;2;3;4) lethal-variegated
    Secondary FlyBase IDs
    • FBal0007916
    References (2)