FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Aberration: Dmel\In(1)wis
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General Information
Symbol
In(1)wis
Species
D. melanogaster
Name
FlyBase ID
FBab0027226
Feature type
chromosomal_inversion
Computed Breakpoints include

3C;20F

Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
wis
(Rasmuson-Lestander et al., 1993)
Mutagen
spontaneous
(Rasmuson-Lestander et al., 1993)
Class of aberration (relative to wild type)
chromosomal_inversion
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_inversion
(Rasmuson-Lestander et al., 1993)
Breakpoints

3C;20F

(Rasmuson-Lestander et al., 1993)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data
Genetic mapping information
Comments
Comments on Cytology

Inversion placing the wis mutation close to heterochromatin. The distal breakpoint is distal to w, and the proximal breakpoint is located proximal to or proximally within the bb locus.

(Rasmuson-Lestander et al., 1993)

All limits from polytene analysis (FBrf0068645)

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
Partially deleted / disrupted
Molecular Data
Completely deleted
Partially deleted
Genes NOT Deleted / Disrupted
Complementation Data
 
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (0)
    If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
    In these cases, there will be no "Export to Hitlist" button to the left.
    Phenotypic Data
    In combination with other aberrations

    The z1 In(1)wis eye colour phenotype is suppressed by Df(YS)B4, Df(YL)S6 and Df(YS)S12, and enhanced by Df(YL)G22 and Df(YL)S10.

    (Rasmuson-Lestander et al., 1993)
    NOT in combination with other aberrations

    The male offspring of In(1)wis z1 females mated to wild-type males have yellow-white variegated eyes. z1 In(1)wis / z1 w+ females have red-orange or orange-yellow variegated eyes. Introduction of Su(z)2unspecified into z1 In(1)wis flies does not alter the background level of pigmentation (white) but darkens the yellow flecks in the eye to orange or red.

    (Rasmuson-Lestander et al., 1993)
    Stocks (0)
    Notes on Origin
    Discoverer
     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     

    The w gene on the In(1)wis chromosome is influenced by position effect variegation and also regulated by chromosome pairing-dependent z1-mediated repression.

    (Rasmuson-Lestander et al., 1993)
    Synonyms and Secondary IDs (1)
    Reported As
    Symbol Synonym
    In(1)wis
    Name Synonyms
    Secondary FlyBase IDs
      References (2)