FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Aberration: Dmel\Df(3L)BSC457
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General Information
Symbol
Df(3L)BSC457
Species
D. melanogaster
Name
FlyBase ID
FBab0045279
Feature type
chromosomal_deletion
Computed Breakpoints include

[68A3-68A3];[68A6-68A6];

Features within 68A3--68A6
Genomic Maps
Sequence coordinates
3L:11,046,246..11,046,246 (Df(3L)BSC457:bk1)
(Bloomington Drosophila Stock Center, 2008.8.7)
3L:11,098,345..11,098,345 (Df(3L)BSC457:bk2)
(Bloomington Drosophila Stock Center, 2008.8.7)
Member of large scale dataset(s)
Dfs_BSC_set2

A set of ~800 largely isogenic deficiency stocks created by FLP-induced recombination between FRT-carrying transgenic insertions; molecularly defined deletion endpoints correspond to initial location of the progenitor insertions. Designed to fill gaps in deletion coverage and breakpoint placement; also used to replace older available deficiencies that have not been molecularly mapped.

(Cook et al., 2012)
Nature of Aberration
Cytological Order
Progenitor
PBac{WH}cochf02990
(Christensen et al., 2008.4.15)
P{XP}d07141
(Christensen et al., 2008.4.15)
Mutagen
FLPase
(Christensen et al., 2008.4.15)
Class of aberration (relative to wild type)
chromosomal_deletion
(Christensen et al., 2008.4.15, FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Christensen et al., 2008.4.15)
Breakpoints

68A3;68A6

(FlyBase Curators, 2008)
Causes alleles
Carries alleles
Transposon Insertions
P+PBac{XP5.WH5}BSC457
(Christensen et al., 2008.4.15)
Formalized genetic data
Genetic mapping information
Comments

Breakpoint based on release 3 sequence coordinate from Thibault et al., 2004, Supplementary Table 2 (FBrf0174227) or 3 (FBrf0174228), converted to release 5 coordinate.

(Bloomington Drosophila Stock Center, 2008.8.7)

Breakpoint from FlyBase's release 5 sequence location of progenitor insertion.

(Bloomington Drosophila Stock Center, 2008.8.7)
Comments on Cytology

The cytological breakpoints of Df(3L)BSC457 predicted from the Release 5 genomic coordinates of the progenitor PBac{WH}CG6327f02990 and P{XP}d07141 insertion sites are 68A3;68A6.

(Christensen et al., 2008.4.15)
Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
Pfdn2
(Christensen et al., 2008.4.15)
Partially deleted / disrupted
Molecular Data
Completely deleted
Partially deleted
Genes NOT Deleted / Disrupted
Complementation Data
 
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (18)
Phenotypic Data
In combination with other aberrations

Inferred to overlap with: Df(3L)BSC674.

(Christensen et al., 2008.12.28)
NOT in combination with other aberrations

Pfdn201239/Df(3L)BSC457 mutants show ectopic neuroblasts in third instar larval brains and an increase in the number of cells in S-phase (assessed by EdU labelling).They also display defects in asymmetric protein segregation (both in metaphase and telophase) and mitotic spindle orientation in neuroblasts.

(Zhang et al., 2016)
Stocks (1)
Notes on Origin
Discoverer
 
Balancer / Genotype Variants of the Aberration
 
Separable Components
 
Other Comments
 

The presence of P+PBac{XP5.WH5}BSC457 was verified using the PCR methods and primers described in FBrf0175003.

(Christensen et al., 2008.4.15)
Synonyms and Secondary IDs (1)
References (9)