FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Gene: Dmel\Irbp18
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General Information
Symbol
Dmel\Irbp18
Species
D. melanogaster
Name
Inverted repeat binding protein 18 kDa
Annotation Symbol
CG6272
Feature Type
protein_coding_gene
FlyBase ID
FBgn0036126
Gene Model Status
Current
Stock Availability
12 publicly available
Gene Summary
bZIP transcription factor - Minute cell competition, arising from mutation of ribosomal proteins, requires the transcription factors Irbp18 and Xrp1 - Xrp1 forms heterodimers with Irbp18, and removal of Irbp18 also strongly suppresses the competitive elimination of Rp/+ cells in mosaic tissues - IRBP18/Xrp1 heterodimer binds sequence-specifically to its dsDNA-binding site within P-element terminal inverted repeats - both proteins are critical for repair of DNA breaks following transposase cleavage in vivo (Interactive Fly, Irbp18 )
Contribute a Gene Snapshot for this gene.
All Summaries
Also Known As

CEBPG

Key Links
Genomic Location
Cytogenetic map
68A6-68A6
Sequence location
Recombination map
3-34
RefSeq locus
NT_037436 REGION:11097446..11098186
Sequence
Get Decorated FASTA
Genomic Maps
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
NCBI
UCSC
Ensembl
PopFly
Function
Gene Ontology (GO) Annotations (10 terms)
Molecular Function (4 terms)
Terms Based on Experimental Evidence (1 term)
CV Term
Evidence
References
enables P-element binding
inferred from direct assay
(Francis et al., 2016)
Terms Based on Predictions or Assertions (3 terms)
CV Term
Evidence
References
enables DNA-binding transcription factor activity, RNA polymerase II-specific
inferred from biological aspect of ancestor with PANTHER:PTN001515662
(GO Reference Genome Project, 2011-)
enables DNA-binding transcription factor activity
inferred from electronic annotation with InterPro:IPR004827, InterPro:IPR031106, InterPro:IPR046347
(InterPro Project Members, 2004-)
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding
inferred from biological aspect of ancestor with PANTHER:PTN001515662
(GO Reference Genome Project, 2011-)
Biological Process (4 terms)
Terms Based on Experimental Evidence (1 term)
CV Term
Evidence
References
involved_in double-strand break repair
inferred from mutant phenotype
(Francis et al., 2016)
Terms Based on Predictions or Assertions (3 terms)
CV Term
Evidence
References
involved_in DNA-templated transcription
inferred from electronic annotation with InterPro:IPR031106
(InterPro Project Members, 2004-)
involved_in regulation of DNA-templated transcription
inferred from electronic annotation with InterPro:IPR004827, InterPro:IPR046347
(InterPro Project Members, 2004-)
involved_in regulation of transcription by RNA polymerase II
inferred from biological aspect of ancestor with PANTHER:PTN001515662
(GO Reference Genome Project, 2011-)
Cellular Component (2 terms)
Terms Based on Experimental Evidence (1 term)
CV Term
Evidence
References
part_of DNA repair complex
inferred from direct assay
(Francis et al., 2016)
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
is_active_in nucleus
inferred from biological aspect of ancestor with PANTHER:PTN001515662
(GO Reference Genome Project, 2011-)
Gene Group (FlyBase)
Protein Family (UniProt)
-
Protein Signatures (InterPro)
Summaries
Gene Group (FlyBase)
BASIC LEUCINE ZIPPER TRANSCRIPTION FACTORS -
The basic leucine zipper (bZIP) transcription factors are sequence-specific DNA-binding proteins that regulate transcription. They are characterized by a 60-80 amino acid bZIP domain: a basic DNA binding domain followed by a leucine zipper dimerization domain. (Adapted from FBrf0152056).
Summary (Interactive Fly)

bZIP transcription factor - Minute cell competition, arising from mutation of ribosomal proteins, requires the transcription factors Irbp18 and Xrp1 - Xrp1 forms heterodimers with Irbp18, and removal of Irbp18 also strongly suppresses the competitive elimination of Rp/+ cells in mosaic tissues - IRBP18/Xrp1 heterodimer binds sequence-specifically to its dsDNA-binding site within P-element terminal inverted repeats - both proteins are critical for repair of DNA breaks following transposase cleavage in vivo

Gene Model and Products
Number of Transcripts
2
Number of Unique Polypeptides
1

Please see the JBrowse view of Dmel\Irbp18 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Structure
Protein 3D structure   (Predicted by AlphaFold)   (AlphaFold entry Q9VTE8)

If you don't see a structure in the viewer, refresh your browser.
Model Confidence:
  • Very high (pLDDT > 90)
  • Confident (90 > pLDDT > 70)
  • Low (70 > pLDDT > 50)
  • Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures
Crossreferences
Comments on Gene Model

Gene model reviewed during 5.45

Gene model reviewed during 5.44

Gene model reviewed during 5.56

Bidirectional region of coding sequence postulated: a portion of the CDS of this gene overlaps a portion of the CDS of a gene on opposite strand.

Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
Irbp18-RA
FBtr0076234
NM_140177
543
113
Irbp18-RB
FBtr0332706
NM_001274769
614
113
Additional Transcript Data and Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
UniProt
RefSeq ID
GenBank
Irbp18-PA
FBpp0075963
13.0
113
9.84
Q9VTE8
NP_648434
AAF50103
Irbp18-PB
FBpp0304952
13.0
113
9.84
Q9VTE8
NP_001261698
AGB94392
Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

113 aa isoforms: Irbp18-PA, Irbp18-PB
Additional Polypeptide Data and Comments
Reported size (kDa)
Comments
External Data
Crossreferences
InterPro - A database of protein families, domains and functional sites
Linkouts
Sequences Consistent with the Gene Model
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Irbp18 using the Feature Mapper tool.

External Data
Crossreferences
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Linkouts
Expression Data
Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

-1.27

Transcript Expression
in situ
Stage
Tissue/Position (including subcellular localization)
Reference
embryonic stage 1 -- 3
organism

Comment: maternally deposited

(Fisher et al., 2012)
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Evidence
References
part_of DNA repair complex
inferred from direct assay
(Francis et al., 2016)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\Irbp18 in JBrowse
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Bulk Downloads
RNA-Seq RPKM values for all genes
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species
EMBL-EBI Single Cell Expression Atlas - Single cell expression across species
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
Flygut - An atlas of the Drosophila adult midgut
Images
FlyBase Wiki
Image Based Resources
Alleles, Insertions, Transgenic Constructs, and Aberrations
Classical and Insertion Alleles ( 2 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 12 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of Irbp18
Transgenic constructs containing regulatory region of Irbp18
Aberrations (Deficiencies and Duplications) ( 0 )
Inferred from experimentation ( 0 )
Inferred from location ( 7 )
Variants
Variant Molecular Consequences
Alleles Representing Disease-Implicated Variants
Phenotypes
Orthologs
Downloads
Download All DIOPT Orthologs
Human Orthologs (via DIOPT v9.1)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
Domainoid
eggNOG
Hieranoid
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Complementation?
Transgene?
Homo sapiens (Human) (20)
Hsap\CEBPG
7 of 14
Yes
Yes
Hsap\CEBPA
3 of 14
No
No
Hsap\CEBPD
3 of 14
No
No
Hsap\CEBPE
3 of 14
No
No
Hsap\CEBPB
2 of 14
No
No
Hsap\DBP
2 of 14
No
No
Hsap\DDIT3
2 of 14
No
Yes
2  
Hsap\HLF
2 of 14
No
No
1  
Hsap\NFIL3
2 of 14
No
No
2  
Hsap\TEF
2 of 14
No
No
Hsap\ATF2
1 of 14
No
No
Hsap\ATF4
1 of 14
No
No
Hsap\ATF7
1 of 14
No
No
1  
Hsap\BATF2
1 of 14
No
No
Hsap\BATF3
1 of 14
No
No
Hsap\BATF
1 of 14
No
No
Hsap\CREB5
1 of 14
No
No
Hsap\JUND
1 of 14
No
No
Hsap\JUN
1 of 14
No
No
Hsap\NFILZ
1 of 14
No
No
Model Organism Orthologs (via DIOPT v9.1)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
Domainoid
eggNOG
Hieranoid
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Complementation?
Transgene?
Rattus norvegicus (Norway rat) (16)
Rnor\Cebpg
7 of 14
Yes
Yes
Rnor\Cebpa
3 of 14
No
No
Rnor\Cebpd
3 of 14
No
No
Rnor\Cebpe
3 of 14
No
No
Rnor\Cebpb
2 of 14
No
No
Rnor\Dbp
2 of 14
No
No
Rnor\Ddit3
2 of 14
No
Yes
Rnor\Nfil3
2 of 14
No
No
Rnor\Tef
2 of 14
No
No
Rnor\Atf4
1 of 14
No
No
Rnor\Atf7
1 of 14
No
No
Rnor\Batf3
1 of 14
No
No
Rnor\Batf
1 of 14
No
No
Rnor\Creb5
1 of 14
No
No
Rnor\Hlf
1 of 14
No
No
Rnor\Jun
1 of 14
No
No
Mus musculus (laboratory mouse) (17)
Mmus\Cebpg
7 of 14
Yes
Yes
Mmus\Cebpb
3 of 14
No
No
Mmus\Cebpe
3 of 14
No
No
Mmus\Cebpa
2 of 14
No
No
Mmus\Cebpd
2 of 14
No
No
Mmus\Dbp
2 of 14
No
No
Mmus\Ddit3
2 of 14
No
Yes
Mmus\Hlf
2 of 14
No
No
Mmus\Nfil3
2 of 14
No
No
Mmus\Tef
2 of 14
No
No
Mmus\Atf4
1 of 14
No
No
Mmus\Atf7
1 of 14
No
No
Mmus\Batf3
1 of 14
No
No
Mmus\Batf
1 of 14
No
No
Mmus\Creb5
1 of 14
No
No
Mmus\Gm4125
1 of 14
No
No
Mmus\Jun
1 of 14
No
No
Xenopus tropicalis (Western clawed frog) (12)
Xtro\cebpg
3 of 13
Yes
Yes
Xtro\atf4
1 of 13
No
No
Xtro\batf
1 of 13
No
No
Xtro\cebpa
1 of 13
No
No
Xtro\cebpb
1 of 13
No
No
Xtro\cebpe
1 of 13
No
No
Xtro\hlf
1 of 13
No
No
Xtro\junb
1 of 13
No
No
Xtro\LOC100486093
1 of 13
No
No
Xtro\shisa1.2
1 of 13
No
Yes
Xtro\tef
1 of 13
No
No
Xtro\thibz
1 of 13
No
No
Danio rerio (Zebrafish) (26)
Drer\cebpg
6 of 14
Yes
Yes
Drer\cebpa
2 of 14
No
No
Drer\cebpb
2 of 14
No
No
Drer\cebpd
2 of 14
No
No
Drer\dbpa
2 of 14
No
No
Drer\dbpb
2 of 14
No
No
Drer\hlfa
2 of 14
No
No
Drer\hlfb
2 of 14
No
No
Drer\nfil3-6
2 of 14
No
No
Drer\nfil3
2 of 14
No
No
Drer\tefa
2 of 14
No
No
Drer\atf2
1 of 14
No
No
Drer\atf7a
1 of 14
No
No
Drer\atf7b
1 of 14
No
No
Drer\batf3
1 of 14
No
No
Drer\batf
1 of 14
No
No
Drer\cebp1
1 of 14
No
No
Drer\creb5b
1 of 14
No
No
Drer\ddit3
1 of 14
No
Yes
Drer\fosaa
1 of 14
No
No
Drer\jun
1 of 14
No
No
Drer\june
1 of 14
No
No
Drer\nfil3-4
1 of 14
No
No
Drer\nfil3-5
1 of 14
No
No
Drer\si:dkey-172o19.2
1 of 14
No
No
Drer\tefb
1 of 14
No
No
Caenorhabditis elegans (Nematode, roundworm) (9)
Cele\cebp-2
7 of 14
Yes
Yes
Cele\atf-2
2 of 14
No
No
Cele\atf-8
2 of 14
No
No
Cele\cebp-1
2 of 14
No
Yes
Cele\ces-2
2 of 14
No
No
Cele\zip-7
2 of 14
No
No
Cele\zip-2
1 of 14
No
Yes
Cele\zip-4
1 of 14
No
Yes
Cele\zip-8
1 of 14
No
Yes
Anopheles gambiae (African malaria mosquito) (9)
Agam\AgaP_AGAP005437
8 of 12
Yes
Yes
Agam\AgaP_AGAP001880
2 of 12
No
No
Agam\AgaP_AGAP007801
2 of 12
No
No
Agam\AgaP_AGAP011096
2 of 12
No
No
Agam\AgaP_AGAP006376
1 of 12
No
No
Agam\AgaP_AGAP007170
1 of 12
No
No
Agam\AgaP_AGAP007171
1 of 12
No
No
Agam\AgaP_AGAP013299
1 of 12
No
No
Agam\AgaP_AGAP013485
1 of 12
No
No
Arabidopsis thaliana (thale-cress) (6)
Atha\bZIP5
1 of 13
Yes
Yes
Atha\bZIP16
1 of 13
Yes
Yes
Atha\bZIP19
1 of 13
Yes
Yes
Atha\bZIP23
1 of 13
Yes
Yes
Atha\BZIP24
1 of 13
Yes
Yes
Atha\HYH
1 of 13
Yes
No
Saccharomyces cerevisiae (Brewer's yeast) (0)
Schizosaccharomyces pombe (Fission yeast) (1)
Spom\atf1
1 of 12
Yes
No
Escherichia coli (enterobacterium) (0)
Other Organism Orthologs (via OrthoDB)
Data provided directly from OrthoDB:Irbp18. Refer to their site for version information.
Paralogs
Downloads
Download All DIOPT Paralogs
Paralogs (via DIOPT v9.1)
Gene Symbol
Score
Source
Compara
Domainoid
eggNOG
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Drosophila melanogaster (Fruit fly) (6)
slbo
3 of 13
CG7786
2 of 13
gt
2 of 13
Pdp1
2 of 13
vri
2 of 13
Mabi
1 of 13
Human Disease Associations
FlyBase Human Disease Model Reports
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Evidence
    References
    Potential Models Based on Orthology ( 0 )
    Human Ortholog
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Interaction
    References
    Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)
    Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
    Homo sapiens (Human)
    Gene name
    Score
    OMIM
    OMIM Phenotype
    DO term
    Complementation?
    Transgene?
    CEBPG; CCAAT enhancer binding protein gamma
    7 of 14
    138972
        CEBPA; CCAAT enhancer binding protein alpha
        3 of 14
        116897
        CEBPD; CCAAT enhancer binding protein delta
        3 of 14
        116898
            CEBPE; CCAAT enhancer binding protein epsilon
            3 of 14
            600749
            Functional Complementation Data
            Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
            Interactions
            Summary of Physical Interactions
            Interaction Browsers
            View in FlyBase Interactions Browser   View in MIST tool (external link)
            Please see the Physical Interaction reports below for full details
            protein-protein
            Physical Interaction
            Assay
            References
            Irbp18 - ATPsynO
            anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based
            (Rhee et al., 2014)
            Irbp18 - Awh
            two hybrid array
            (Shokri et al., 2019)
            Irbp18 - BEAF-32
            two hybrid array
            (Shokri et al., 2019)
            Irbp18 - Blimp-1
            two hybrid array
            (Shokri et al., 2019)
            Irbp18 - BuGZ
            anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based
            (Rhee et al., 2014)
            Irbp18 - CG10654
            two hybrid array
            (Shokri et al., 2019)
            Irbp18 - CG10669
            two hybrid array
            (Shokri et al., 2019)
            Irbp18 - CG11723
            two hybrid array
            (Shokri et al., 2019)
            Irbp18 - CG13204
            two hybrid array
            (Shokri et al., 2019)
            Irbp18 - CG15710
            two hybrid array
            (Shokri et al., 2019)
            Irbp18 - CG15812
            two hybrid array
            (Shokri et al., 2019)
            Irbp18 - CG17287
            two hybrid array
            (Shokri et al., 2019)
            Irbp18 - CG17803
            two hybrid array
            (Shokri et al., 2019)
            Irbp18 - CG18599
            two hybrid array
            (Shokri et al., 2019)
            Irbp18 - CG2712
            two hybrid array
            (Shokri et al., 2019)
            Irbp18 - CG31365
            two hybrid array
            (Shokri et al., 2019)
            Irbp18 - CG32767
            two hybrid array
            (Shokri et al., 2019)
            Irbp18 - CG3919
            two hybrid array
            (Shokri et al., 2019)
            Irbp18 - CG6470
            two hybrid array
            (Shokri et al., 2019)
            Irbp18 - CG6769
            anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based
            (Rhee et al., 2014)
            Irbp18 - CG7786
            two hybrid array
            (Shokri et al., 2019)
            Irbp18 - CG8089
            two hybrid array
            (Shokri et al., 2019)
            Irbp18 - CG8319
            two hybrid array
            (Shokri et al., 2019)
            Irbp18 - CG8924
            two hybrid array
            (Shokri et al., 2019)
            Irbp18 - CG9215
            two hybrid array
            (Shokri et al., 2019)
            Irbp18 - Cf2
            two hybrid array
            (Shokri et al., 2019)
            Irbp18 - Chrac-14
            two hybrid array
            (Shokri et al., 2019)
            Irbp18 - D19B
            two hybrid array
            (Shokri et al., 2019)
            Irbp18 - E2f2
            two hybrid array
            (Shokri et al., 2019)
            Irbp18 - E5
            two hybrid array
            (Shokri et al., 2019)
            Irbp18 - Evi5
            two hybrid
            (Hu et al., 2017.6.13)
            Irbp18 - H2.0
            two hybrid array
            (Shokri et al., 2019)
            Irbp18 - Hr78
            two hybrid array
            (Shokri et al., 2019)
            Irbp18 - Klf15
            two hybrid array
            (Shokri et al., 2019)
            Irbp18 - Lime
            two hybrid array
            (Shokri et al., 2019)
            Irbp18 - MBD-R2
            two hybrid array
            (Shokri et al., 2019)
            Irbp18 - Mad
            two hybrid array
            (Shokri et al., 2019)
            Irbp18 - Mad1
            two hybrid
            (Hu et al., 2017.6.13)
            Irbp18 - Max
            two hybrid array
            (Shokri et al., 2019)
            Irbp18 - NfI
            two hybrid array
            (Shokri et al., 2019)
            Irbp18 - PolE4
            two hybrid array
            (Shokri et al., 2019)
            Irbp18 - Rbsn-5
            two hybrid array
            (Shokri et al., 2019)
            Irbp18 - Rx
            two hybrid array
            (Shokri et al., 2019)
            Irbp18 - Sox102F
            two hybrid array
            (Shokri et al., 2019)
            Irbp18 - Xrp1
            anti tag coimmunoprecipitation, Identification by mass spectrometry, bimolecular fluorescence complementation, fluorescence microscopy, fluorescent resonance energy transfer, pull down, molecular weight estimation by staining, ion exchange chromatography, molecular sieving, western blot, two hybrid array
            (Shokri et al., 2019, Francis et al., 2016, Reinke et al., 2013)
            Irbp18 - Zaf1
            two hybrid array
            (Shokri et al., 2019)
            Irbp18 - ara
            two hybrid array
            (Shokri et al., 2019)
            Irbp18 - ase
            two hybrid array
            (Shokri et al., 2019)
            Irbp18 - chn
            two hybrid array
            (Shokri et al., 2019)
            Irbp18 - comr
            two hybrid array
            (Shokri et al., 2019)
            Irbp18 - crc
            two hybrid, fluorescent resonance energy transfer
            (Hu et al., 2017.6.13, Reinke et al., 2013)
            Irbp18 - da
            two hybrid array
            (Shokri et al., 2019)
            Irbp18 - dmrt11E
            two hybrid array
            (Shokri et al., 2019)
            Irbp18 - drm
            two hybrid array
            (Shokri et al., 2019)
            Irbp18 - dsx
            two hybrid array
            (Shokri et al., 2019)
            Irbp18 - gcm2
            two hybrid array
            (Shokri et al., 2019)
            Irbp18 - grh
            two hybrid array
            (Shokri et al., 2019)
            Irbp18 - gro
            two hybrid array
            (Shokri et al., 2019)
            Irbp18 - hth
            two hybrid array
            (Shokri et al., 2019)
            Irbp18 - jing
            two hybrid array
            (Shokri et al., 2019)
            Irbp18 - l(2)k10201
            two hybrid array
            (Shokri et al., 2019)
            Irbp18 - lbe
            two hybrid array
            (Shokri et al., 2019)
            Irbp18 - lmd
            two hybrid array
            (Shokri et al., 2019)
            Irbp18 - ro
            two hybrid array
            (Shokri et al., 2019)
            Irbp18 - slbo
            two hybrid array
            (Shokri et al., 2019)
            Irbp18 - sob
            two hybrid array
            (Shokri et al., 2019)
            Irbp18 - soul
            two hybrid array
            (Shokri et al., 2019)
            Irbp18 - tap
            two hybrid array
            (Shokri et al., 2019)
            Irbp18 - tgo
            two hybrid array
            (Shokri et al., 2019)
            Irbp18 - zen
            two hybrid array
            (Shokri et al., 2019)
            Summary of Genetic Interactions
            Interaction Browsers
            Starting gene(s)
            Interaction type
            Interacting gene(s)
            Reference
            Starting gene(s)
            Interaction type
            Interacting gene(s)
            Reference
            External Data
            Linkouts
            DroID - A comprehensive database of gene and protein interactions.
            MIST (protein-protein) - An integrated Molecular Interaction Database
            Pathways
            Signaling Pathways (FlyBase)
            Metabolic Pathways
            FlyBase
            External Links
            External Data
            Linkouts
            Class of Gene
            Genomic Location and Detailed Mapping Data
            Chromosome (arm)
            3L
            Recombination map
            3-34
            Cytogenetic map
            68A6-68A6
            Sequence location
            FlyBase Computed Cytological Location
            Cytogenetic map
            Evidence for location
            68A6-68A6
            Limits computationally determined from genome sequence between P{PZ}l(3)0123901239&P{lacW}l(3)01239j9B4 and P{PZ}CycA02461&P{PZ}CycA03946
            Experimentally Determined Cytological Location
            Cytogenetic map
            Notes
            References
            Experimentally Determined Recombination Data
            Location

            3-34

            (FlyBase, 2016)

            3-28.4

            (Comeron et al., 2012)
            Left of (cM)
            Right of (cM)
            Notes
            Stocks and Reagents
            Stocks (12)
            Genomic Clones (17)
             

            Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

            cDNA Clones (4)
             

            Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

            cDNA clones, fully sequenced
            BDGP DGC clones
            Other clones
            Drosophila Genomics Resource Center cDNA clones

            For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

            cDNA Clones, End Sequenced (ESTs)
            BDGP DGC clones
              Other clones
              RNAi and Array Information
              Linkouts
              DRSC - Results frm RNAi screens
              Antibody Information
              Laboratory Generated Antibodies
               

              polyclonal

              (Francis et al., 2016)
              Commercially Available Antibodies
               
              Cell Line Information
              Publicly Available Cell Lines
               
                Other Stable Cell Lines
                 
                Other Comments
                Relationship to Other Genes
                Source for database merge of

                Source for merge of: CG6272 BcDNA:GH10915

                (FlyBase, 1996-)
                Additional comments

                Source for merge of CG6272 BcDNA:GH10915 was a shared cDNA ( date:030728 ).

                (FlyBase, 1996-)
                Nomenclature History
                Source for database identify of

                Source for identity of: Irbp18 CG6272

                (Francis et al., 2016)
                Nomenclature comments
                Etymology

                The gene is named 'Irbp18' based on sequence-specific binding to P-element 31bp terminal inverted repeats.

                (Francis et al., 2016)
                Synonyms and Secondary IDs (10)
                Datasets (0)
                Study focus (0)
                Experimental Role
                Project
                Project Type
                Title
                Study result (0)
                Result
                Result Type
                Title
                External Crossreferences and Linkouts ( 35 )
                Sequence Crossreferences
                NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
                GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
                GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
                RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
                UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.
                UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information
                Other crossreferences
                AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.
                BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
                DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species
                EMBL-EBI Single Cell Expression Atlas - Single cell expression across species
                FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
                FlyMine - An integrated database for Drosophila genomics
                InterPro - A database of protein families, domains and functional sites
                KEGG Genes - Molecular building blocks of life in the genomic space.
                MARRVEL_MODEL - MARRVEL (model organism gene)
                Linkouts
                Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
                DroID - A comprehensive database of gene and protein interactions.
                DRSC - Results frm RNAi screens
                Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
                FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
                FlyCyc Genes - Genes from a BioCyc PGDB for Dmel
                Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
                Flygut - An atlas of the Drosophila adult midgut
                iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)
                Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution
                MIST (protein-protein) - An integrated Molecular Interaction Database
                References (76)