FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Aberration: Dmel\Df(2L)LanB1
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General Information
Symbol
Df(2L)LanB1
Species
D. melanogaster
Name
FlyBase ID
FBab0046276
Feature type
chromosomal_deletion
Also Known As
LanB1DEF
Computed Breakpoints include
Features within 28C4--28D1 (Estimated cytology)
Genomic Maps
Sequence coordinates
2L:7,809,094..7,809,094 (Df(2L)LanB1:bk1)
(Urbano et al., 2009)
2L:7,820,680..7,820,680 (Df(2L)LanB1:bk2)
(Urbano et al., 2009)
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
PBac{RB}LanB1e02263
(Urbano et al., 2009)
P{XP}Cdc14d04880
(Urbano et al., 2009)
Mutagen
recombination
(Urbano et al., 2009)
Class of aberration (relative to wild type)
chromosomal_deletion
(Urbano et al., 2009)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Urbano et al., 2009)
Breakpoints
Causes alleles
Cdc14Δ5'
(Urbano et al., 2009)
Carries alleles
Transposon Insertions
Formalized genetic data
Genetic mapping information
Comments

Recombination between the two progenitor insertions has resulted in deletion of the genomic sequence between them, removing the entire LanB1 gene and the 5'UTR of cdc14.

(Urbano et al., 2009)

Reported as a deletion generated by recombination between P{XP}cdc14d04880 and PBac{RB}LanB1e02263.

(Urbano et al., 2009)
Comments on Cytology
Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
Partially deleted / disrupted
Molecular Data
Completely deleted
LanB1
(Urbano et al., 2009)
Partially deleted
Cdc14
(Urbano et al., 2009)
Genes NOT Deleted / Disrupted
Complementation Data
 
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (2)
Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations

Df(2L)LanB1 homozygotes exhibit basement membrane discontinuity in the larval fat body, unlike controls.

(Dai et al., 2018)

The ventral nerve cord of homozygous Df(2L)LanB1 embryos fail to condense, and display irregular morphology of the cardiac tube. Late stage Df(2L)LanB1 homozygotes show either no basement membranes or disorganised and diffuse extracellular matrix material associated with various tissues, such as the visceral musculature surrounding the midgut or hindgut, the Malphigian tubules or the perineural cells of the central nervous system. Adult wings with large homozygous Df(2L)LanB1 clones show a wing blister phenotype.

(Urbano et al., 2009)
Stocks (1)
Notes on Origin
Discoverer
 
Balancer / Genotype Variants of the Aberration
 
Separable Components
 
Other Comments
 
Synonyms and Secondary IDs (5)
Reported As
Symbol Synonym
Df LanB1
(Dai et al., 2018)
Df(2L)LanB1
(Matsubayashi et al., 2017)
LanB1DEF
(Urbano et al., 2009)
lanB1DEF
(Koper et al., 2012)
ΔLanB1
(Matsubayashi et al., 2017)
Name Synonyms
Secondary FlyBase IDs
    References (4)