FB2026_03 , released September 17, 2026
Aberration: Dmel\Df(2L)CycYE8
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General Information
Symbol
Df(2L)CycYE8
Species
D. melanogaster
Name
FlyBase ID
FBab0046626
Feature type
chromosomal_deletion
Computed Cytological Breakpoints (relative to progenitor)
Features within 33A2--33A2 (Estimated cytology)
Sequenced Breakpoints (relative to progenitor)
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
P{XP}crold03228
(Liu and Finley, 2010)
Mutagen
Delta2-3 transposase
(Liu and Finley, 2010)
Class of aberration (relative to wild type)
chromosomal_deletion
(Liu and Finley, 2010)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Liu and Finley, 2010)
Cytological Breakpoints (relative to progenitor)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data
Genetic mapping information
Comments

Two-part deletion resulting from the imprecise excision of P{XP}crold03228. One part is 6119bp and extends from 734bp downstream of the Pde1c stop codon to 1411bp downstream of the CycY stop codon and the other is 988bp and extends from 1955bp downstream of the CycY stop codon to the first noncoding exon of crol.

(Liu and Finley, 2010)
Comments on Cytology
Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
Partially deleted / disrupted
Molecular Data
Completely deleted
CycY
(Liu and Finley, 2010)
Partially deleted
crol
(Liu and Finley, 2010)
Pde1c
(Liu and Finley, 2010)
Genes NOT Deleted / Disrupted
Complementation Data
 
crol
(Liu and Finley, 2010)
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (0)
    If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
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    Phenotypic Data
    In combination with other aberrations

    Inferred to overlap with: Df(2L)Exel6030.

    (Liu and Finley, 2010)
    NOT in combination with other aberrations

    Homozygous Df(2L)CycYE8 mutants produce no viable adults.

    Homozygous Df(2L)CycYE8 mutants display two major lethal phase during metamorphosis. The early lethal phase is between pupal stages P3 and P5. The late lethal phase of homozygous Df(2L)CycYE8 mutants is between pupal stages P14 and P15.

    Homozygous Df(2L)CycYE8 mutants show metamorphosis defects including the failure of proper gas bubble translocation, failed head eversion, and the failure of proper leg elongation. In addition, pupae of Homozygous Df(2L)CycYE8 mutants are small in weight and length. Homozygous Df(2L)CycYE8 mutants mutants exhibit delayed larval development and puparium formation.

    About 40 % of the eggs produced by female germ-line mutant clones of Df(2L)CycYE8 exhibit fused dorsal appendages.

    The majority of maternal and zygotic Df(2L)CycYE8 mutant embryos fail to hatch.

    (Liu and Finley, 2010)
    Stocks (0)
    Notes on Origin
    Discoverer
     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     
    Synonyms and Secondary IDs (3)
    Reported As
    Symbol Synonym
    CycYE8
    (Liu and Finley, 2010)
    Df(2L)CycYE8
    E8
    (Liu and Finley, 2010)
    Name Synonyms
    Secondary FlyBase IDs
      References (1)