FB2026_02 , released June 18, 2026
Aberration: Dmel\Df(2R)Dm310s
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General Information
Symbol
Df(2R)Dm310s
Species
D. melanogaster
Name
FlyBase ID
FBab0046906
Feature type
Computed Breakpoints include
Features within 57A6--57A6 (Estimated cytology)
Genomic Maps
Sequence coordinates
2R:20,582,922..20,582,922 (Df(2R)Dm310s:bk1)
(Tang et al., 2010)
2R:20,584,337..20,584,337 (Df(2R)Dm310s:bk2)
(Tang et al., 2010)
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
P{EP}qsmEP2587
(Tang et al., 2010)
Mutagen
Delta2-3 transposase
(Tang et al., 2010)
Class of aberration (relative to wild type)
Class of aberration (relative to progenitor)
Breakpoints
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data
Genetic mapping information
Comments

Estimated location of a 1416bp deletion resulting from the imprecise excision of P{EP}qsmEP2587 that removes the whole "mir310s" cluster leaving the flanking genes intact. It was not specified if the P element removed sequences in one or both directions from the insertion site.

(Tang et al., 2010)
Comments on Cytology
Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
Partially deleted / disrupted
Molecular Data
Completely deleted
mir-310
(Tang et al., 2010)
mir-311
(Tang et al., 2010)
mir-312
(Tang et al., 2010)
mir-313
(Tang et al., 2010)
Partially deleted
Genes NOT Deleted / Disrupted
Complementation Data
 
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (0)
    If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
    In these cases, there will be no "Export to Hitlist" button to the left.
    Phenotypic Data
    In combination with other aberrations
    NOT in combination with other aberrations

    Df(2R)Dm310s mutant flies produce eggs with deformed dorsal appendages (shorter with smaller paddle regions) and strongly reduced hatchability compared to wild-type eggs. Df(2R)Dm310s males have reduced fertility (assayed under sperm-depletion conditions). All these phenotypes can be rescued by combination with either P{UAS-miR310s} or P{UAS-Dp310s.Dpse}, constructs carrying the 'Dm310s' mir cluster (mir-310, mir-311, mir-312 and mir-313 under UAS control) or the 'Dp310s' mir cluster from Drosophila pseudoobscura (Dpse mir-310, mir-311 and mir-312 under UAS control), respectively, although the fertility rescue with P{UAS-Dp310s.Dpse} is only partial.

    (Liufu et al., 2017)

    Homozygous Df(2R)Dm310s flies do not display any detectable reduction in viability compared to wild-type controls. Female fecundity of homozygous Df(2R)Dm310s flies is decreased compared to controls.

    (Tang et al., 2010)
    Stocks (0)
    Notes on Origin
    Discoverer
     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     

    A 1,416-bp deletion removing the cluster composed of mir-310, mir-311, mir-312 and mir-313 with the flanking genes intact.

    (Tang et al., 2010)
    Synonyms and Secondary IDs (4)
    Reported As
    Symbol Synonym
    Df(2R)Dm310s
    Dm310s(-)
    (Tang et al., 2010)
    miR310s-KO
    (Ma et al., 2018)
    mir310s-
    (Liufu et al., 2017)
    Name Synonyms
    Secondary FlyBase IDs
      References (3)