FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Aberration: Dmel\Df(2R)BomΔ55C
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General Information
Symbol
Df(2R)BomΔ55C
Species
D. melanogaster
Name
FlyBase ID
FBab0047701
Feature type
chromosomal_deletion
Also Known As
BomΔ55C
Computed Breakpoints include
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Mi{MIC}BomS2MI01019
(Clemmons et al., 2015)
Mutagen
TALEN
(Clemmons et al., 2015)
Class of aberration (relative to wild type)
chromosomal_deletion
(Clemmons et al., 2015)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Clemmons et al., 2015)
Breakpoints
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data
Genetic mapping information
Comments

9kb deletion of the ten genes in the 55C 'Bom' cluster, generated from the progenitor insertion using a TALEN approach.

(Clemmons et al., 2015)
Comments on Cytology
Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Genes NOT Deleted / Disrupted
Complementation Data
 
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (0)
    If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
    In these cases, there will be no "Export to Hitlist" button to the left.
    Phenotypic Data
    In combination with other aberrations
    NOT in combination with other aberrations

    Df(2R)BomΔ55C adults exhibit increased mortality as a result of Candida glabrata, Fusarium oxysporum or Enterococcus faecalis (alive but not heat-killed) but not Enterobacter cloacae or heat-killed Micrococcus luteus infection when compared to controls.

    The pathogen loads of early deaths for Df(2R)BomΔ55C adults are not significantly different than controls.

    (Lin et al., 2019)

    Df(2R)BomΔ55C individuals show lower survival to infection with Candida glabrata, as compared to controls. Unlike wild-type controls, their hemolymph is fungicidal either at room temperature for 1h or at 4[o]C for 24h.

    (Lindsay et al., 2018)

    Compared to wild type controls, adult Df(2R)BomΔ55C flies are much more susceptible to septic infection by the Enterococcus faecalis bacterium, the yeast Candida glabrata or the filamentous fungus Fusarium oxysporum. In contrast, septic infection with the Enterobacter cloacae bacterium has no significant effect on survival.

    Df(2R)BomΔ55C flies show an elevated bacterial load above that of control levels during the course of Enterococcus faecalis infection, indicative of a defect in infection resistance.

    (Clemmons et al., 2015)
    Stocks (0)
    Notes on Origin
    Discoverer
     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     
    Synonyms and Secondary IDs (4)
    References (9)