A 4.3 kb deletion that removes the first 433 amino-terminal codons of the Gba1b gene and the carboxy-terminal 33 codons of the Gba1a gene, and completely removes the intervening gene, Qsox4. This deletion allele results in the production of a hybrid transcript fusing the amino terminal Gba1a coding sequence to the carboxy terminal Gba1b sequences, but does not create an in-frame fusion of the coding sequences, and therefore is not expected to yield a chimeric glucocerebrosidase protein. Given that this deletion eliminates the presumptive promoter and >3/4 of the amino terminal coding sequence of Gba1b, and results in ~75% reduced expression of a transcript lacking the final 33 codons of Gba1a, it is likely a null allele of Gba1b and a hypomorphic allele of Gba1a. The residual expression of the fusion transcript is nearly undetectable in heads from homozygotes.

FlyBase curator comment: Deletion endpoints are inferred from the reported description as having the carboxy-terminal 33 codons of Gba1a and the amino-terminal 433 codons of Gba1b as well as the intervening Qsox4 gene removed.