FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Aberration: Dmel\Df(2R)reb-64
Open Close
General Information
Symbol
Df(2R)reb-64
Species
D. melanogaster
Name
FlyBase ID
FBab0049022
Feature type
chromosomal_deletion
Computed Breakpoints include
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
P{GawB}MCPH1NP6229
(Chandran et al., 2018)
Mutagen
Delta2-3 transposase
(Chandran et al., 2018)
Class of aberration (relative to wild type)
chromosomal_deletion
(Chandran et al., 2018)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Chandran et al., 2018)
Breakpoints
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data
Genetic mapping information
Comments

Deletion that completely removes the reb gene as well as disrupting MCPH1 and Zip48C.

(Chandran et al., 2018)
Comments on Cytology
Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
Partially deleted / disrupted
Molecular Data
Completely deleted
reb
(Chandran et al., 2018)
Partially deleted
Genes NOT Deleted / Disrupted
Complementation Data
 
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (0)
    If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
    In these cases, there will be no "Export to Hitlist" button to the left.
    Phenotypic Data
    In combination with other aberrations

    The dorsal trunk of the tracheal system in Df(2R)reb-64/Df(2R)BSC879 embryos is curly, slightly irregular and elongated compared to controls. Despite its change in size, the tracheal network has normal branching patterns.

    (Chandran et al., 2018)
    NOT in combination with other aberrations

    The dorsal trunk of the tracheal system in Df(2R)reb-64 homozygous embryos is curly, slightly irregular and elongated compared to controls. Despite its change in size, the tracheal network has normal branching patterns.

    Cell polarity is maintained in the dorsal trunk of the tracheal system in embryos homozygous for Df(2R)reb-64.

    Extracellular matrix components are drastically reduced and endocytosis is disrupted in the apical membrane of the tracheal lumen in Df(2R)reb-64 homozygous embryos.

    (Chandran et al., 2018)
    Stocks (0)
    Notes on Origin
    Discoverer
     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     
    Synonyms and Secondary IDs (2)
    Reported As
    Symbol Synonym
    Df(2R)reb-64
    reb64
    (Chandran et al., 2018)
    Name Synonyms
    Secondary FlyBase IDs
      References (1)