FB2026_03 , released September 17, 2026
Aberration: Dmel\In(1)FM8
Open Close
General Information
Symbol
In(1)FM8
Species
D. melanogaster
Name
FlyBase ID
FBab0049294
Feature type
chromosome_structure_variation
Computed Cytological Breakpoints (relative to progenitor)
Sequenced Breakpoints (relative to progenitor)
X:7,535,590..7,535,590 (In(1)FM8:bk1)
(Muron et al., 2022)
X:2,795,833..2,795,833 (In(1)FM8:bk2)
(Muron et al., 2022)
Member of large scale dataset(s)
Nature of Aberration
Cytological Order

1Lt-1B2 | 20F-20A | 15D-20A | 15D-11F4 | 4E1-7B4 | 3B6-4D7 | 11F2-7B4 | 3B6-1B3 | 20F-1Rt

(Muron et al., 2022)
Progenitor
In(1)FM7a
(Muron et al., 2022)
Mutagen
CRISPR/Cas9
(Muron et al., 2022)
Class of aberration (relative to wild type)
chromosome_structure_variation
(Muron et al., 2022)
Class of aberration (relative to progenitor)
chromosomal_inversion
(Muron et al., 2022)
Cytological Breakpoints (relative to progenitor)
Causes alleles
ctFM8
(Muron et al., 2022)
wFM8
(Muron et al., 2022)
Carries alleles
Transposon Insertions
Formalized genetic data
Genetic mapping information
Comments

The 5' (distal) end of this breakpoint corresponds to X:2795833 and the 3' end (proximal) corresponds to X:2795820 (release 6 coordinates), meaning that 12bp of genomic sequence is deleted at this breakpoint.

(Muron et al., 2022)

The 5' (distal) end of this breakpoint corresponds to X:7535590 and the 3' end (proximal) corresponds to X:7535595 (release 6 coordinates), meaning that 4bp of genomic sequence is deleted at this breakpoint.

(Muron et al., 2022)
Comments on Cytology
Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
ct
(Muron et al., 2022)
w
(Muron et al., 2022)
Partially deleted / disrupted
Molecular Data
Completely deleted
Partially deleted
Genes NOT Deleted / Disrupted
Complementation Data
 
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (0)
    If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
    In these cases, there will be no "Export to Hitlist" button to the left.
    Phenotypic Data
    In combination with other aberrations
    NOT in combination with other aberrations

    Hemizygous and homozygous lethal.

    (Muron et al., 2022)
    Stocks (0)
    Notes on Origin
    Discoverer
     

    CRISPR/Cas9 was used to generate an additional inversion in the FM7c variant of FM7a by cutting at ct (at 7B4 inside the 4E1-11F2 inversion) and w (at 3B6 inside the 4D7-1B3 inversion) (FBrf0255123).

    (Parks and Cook, 2026.8.6)
    Balancer / Genotype Variants of the Aberration
    Separable Components
     
    Other Comments
     
    Synonyms and Secondary IDs (2)
    Reported As
    Symbol Synonym
    FM8
    (Parks and Cook, 2026.8.6)
    In(1)FM8
    (Muron et al., 2022)
    Name Synonyms
    Secondary FlyBase IDs
      References (3)