FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Abd-Biab7-SGA
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General Information
Symbol
Dmel\Abd-Biab7-SGA
Species
D. melanogaster
Name
FlyBase ID
FBal0000131
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
iab7SGA62, iab-7SGA62, SGA62
Key Links
Mutagen
Nature of the Allele
Progenitor genotype
Caused by aberration
Cytology
Description

Molecular lesion maps at 133-139.5kb.

Breakpoint maps to between coordinates +133 and +139.5kb.

Lesion mapped to: 133-139.5 kb.

Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference

Abd-B protein is observed in parasegments 13-15 but not in parasegments 11 and 12 in the ectoderm and in the CNS.

Abd-B transcripts are observed in parasegments 13-15 but not in parasegments 11 and 12.

 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Hemizygotes show an iab5,6,7 mutant phenotype: abdominal segments A5-A7 transform towards A4. Heterozygotes with Abd-B point or pseudopoint mutations cause a less severe mutant phenotype, with mixed A5/A6 identity in A6 and A7. Phenotype over UbxMX12, abd-AM1, Abd-BM8 is the same as when over Abd-B-.

Heterozygous show a transformation of head structures into genital and abdominal structures; structures characteristic of the 7th or 8th abdominal segments as well as of the lateral plates of the genitalia can often be recognised in the head. In males the transformed head parts show the dark pigmentation characteristic of the male abdomen. The occiput, upper postorbita and facets are transformed most frequently, the vertex, frontorbita and frons are rarely transformed, and the lower postorbita, ptilinum and vibrissae are not transformed. Antennal structures are sometimes found in the middle of the eyes. Eye-antennal discs appear abnormal; the lateral part is flattened without any significant folding. The penetrance of the phenotype is nearly complete at 25oC, somewhat lower at 18oC, and significantly reduced at 29oC. 84.2% of the progeny of heterozygous females show the head transformation phenotype, indicating that this mutation has a maternal enhancement effect. Homozygotes have reduced viability and are sterile. They also have abnormal head morphology; a small group of facets form instead of the eyes, and the occiput bristles, ocelli and antennae are missing.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

tuh1h/tuh1h Abd-Biab7-SGA/Abd-Biab9-tuh-3 flies have a similar phenotype to Abd-Biab7-SGA heterozygotes.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer

Gyurkovics.

Comments
Comments

Expression of Abd-B protein and mRNA is limited to parasegments 13-15.

m- r+ mutant, with defect in spatial regulation of Abd-B function.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (6)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (7)