FB2026_02 , released June 18, 2026
Allele: Dmel\Adhn2
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General Information
Symbol
Dmel\Adhn2
Species
D. melanogaster
Name
FlyBase ID
FBal0000333
Feature type
allele
Associated gene
Dmel\Adh
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

amorphic allele - genetic evidence

loss of function allele

Mutagen
Nature of the Allele
Allele class

amorphic allele - genetic evidence

(Kapoun et al., 1990, Hollocher and Place, 1987, Woodruff and Ashburner, 1979)

loss of function allele

(Meister and Grigliatti, 1993)
Mutagen
ethyl methanesulfonate
(Kapoun et al., 1990)
Progenitor genotype
AdhS
(Chenevert et al., 1995)
Cytology
Description

Amino acid replacement: A159T. Nucleotide substitution: G1317A.

(Chenevert et al., 1995)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
2L:14,616,878..14,616,878 [+]
Nucleotide change:

G14616878A

Reported nucleotide change:

G1317A

Amino acid change:

A159T | Adh-PC; A159T | Adh-PE; A159T | Adh-PF; A159T | Adh-PH; A159T | Adh-PI

Reported amino acid change:

A159T

Comment:

Induced on an AdhS chromosome.

(Chenevert et al., 1995)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (14)
      Notes on Origin
      Discoverer

      E.H. Grell.

      Comments
      Comments

      CRM: 5% of wild type progenitor. Product does not form active hybrid enzyme.

      The effect of dietary sucrose and ethanol on Gpdh activity in Adhn2 third instar larvae has been studied.

      (Geer et al., 1983)

      Product does not form active hybrid enzyme.

      (Hollocher and Place, 1987)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Adhn2
      Name Synonyms
      Secondary FlyBase IDs
        References (16)