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General Information
Symbol
Dmel\Adhn4
Species
D. melanogaster
Name
FlyBase ID
FBal0000335
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Nucleotide change:

C14616650T

Reported nucleotide change:

C312T

Amino acid change:

Q83term | Adh-PC; Q83term | Adh-PE; Q83term | Adh-PF; Q83term | Adh-PH; Q83term | Adh-PI

Reported amino acid change:

Q83term

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

A premature stop codon located 258bp upstream from the boundary between exon 3 and exon 4.

Steady state level of Adh mRNA is greatly reduced.

Nucleotide substitution: C312T.

Amino acid replacement: Q83term.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Oviposition sites on standard medium and acetic acid supplement medium are studied.

Sensitive to pentenol. Not sensitive to pentenone.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (18)
Notes on Origin
Discoverer

E.H. Grell.

Comments
Comments

CRM negative.

No detectable protein.

Product does not form active hybrid enzyme.

Adhn4 mRNA is only 10% of wild type levels. S1 nuclease protection studies show the processing of the Adhn4 transcript to be normal.

External Crossreferences and Linkouts ( 1 )
Crossreferences
GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
Synonyms and Secondary IDs (2)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (27)