loss of function allele
amorphic allele - genetic evidence
Q83term | Adh-PC; Q83term | Adh-PE; Q83term | Adh-PF; Q83term | Adh-PH; Q83term | Adh-PI
A premature stop codon located 258bp upstream from the boundary between exon 3 and exon 4.
Steady state level of Adh mRNA is greatly reduced.
Nucleotide substitution: C312T.
Amino acid replacement: Q83term.
Oviposition sites on standard medium and acetic acid supplement medium are studied.
Sensitive to pentenol. Not sensitive to pentenone.
No detectable protein.
Product does not form active hybrid enzyme.
Adhn4 mRNA is only 10% of wild type levels. S1 nuclease protection studies show the processing of the Adhn4 transcript to be normal.