FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\apb1
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General Information
Symbol
Dmel\apb1
Species
D. melanogaster
Name
FlyBase ID
FBal0000664
Feature type
allele
Associated gene
apb
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
U.V.
(Meyer et al., 1950)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Wings are always notched, nearly always spread and usually blistered, but expression is somewhat variable. Homozygous imagos live less than 24 hours, due to intestinal obstructions that prevent defecation. Abdomens characteristically turn dark grey before death because of accumulation of digested food products.

      (Meyer et al., 1950)

      RK2.

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Other
      Statement
      Reference

      ap4, apb[+]/apb1 has fertile phenotype

      (Meyer et al., 1950)

      ap4, apb[+]/apb1 has visible | dominant phenotype

      (Meyer et al., 1950)

      ap[+]/ap4, apb1 has fertile phenotype

      (Meyer et al., 1950)

      ap[+]/ap4, apb1 has visible | dominant phenotype

      (Meyer et al., 1950)
      Phenotype Manifest In
      Enhanced by
      Statement
      Reference

      apb1 has phenotype, enhanceable by ap5

      (Meyer et al., 1950)
      Enhancer of
      Statement
      Reference

      apb1 is an enhancer of phenotype of ap5

      (Meyer et al., 1950)

      apb1 is an enhancer of phenotype of ap4

      Other
      Statement
      Reference

      ap4, apb[+]/apb1 has wing phenotype

      (Meyer et al., 1950)

      ap[+]/ap4, apb1 has wing phenotype

      (Meyer et al., 1950)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      apb1/ap4 double heterozygotes show slight notching of the wings and many die within a day, but those that survive are fertile. apb1/ap5 flies show a similar combination of effects.

      (Meyer et al., 1950)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Edmondson, Nov. 1949

      (Meyer et al., 1950)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      apb
      (Meyer et al., 1950)
      apb1
      Name Synonyms
      Secondary FlyBase IDs
        References (2)