FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\ast2
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General Information
Symbol
Dmel\ast2
Species
D. melanogaster
Name
FlyBase ID
FBal0000775
Feature type
allele
Associated gene
Dmel\ast
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
spontaneous
(Lewis, 1945)
Progenitor genotype
Cytology

Polytene chromosomes normal.

(Lewis, 1945)
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygotes have a similar eye phenotype to ast1, but wing venation is normal.

      (Lewis, 1945)

      S1/ast2 lethal. Heterozygote strongly enhanced by E(S). RK2A.

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhanced by
      Statement
      Reference

      ast2 has visible phenotype, enhanceable by E(S)1

      (Lewis, 1945)
      Other
      Statement
      Reference

      S1, ast2 has lethal | dominant phenotype

      (Lewis, 1945)
      Phenotype Manifest In
      Enhanced by
      Statement
      Reference

      ast2 has eye phenotype, enhanceable by E(S)1

      (Lewis, 1945)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Lethal in double heterozygous combination with S1. The phenotype is dominantly enhanced by E(S)1; ast1 E(S)1 double heterozygotes have rough eyes.

      (Lewis, 1945)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      E.H. Grell, June 1965.

      Arose on: In(2L)Cy.

      Arose in: In(2L)Cy.

      (Lewis, 1945)
      Comments
      Comments

      Similar to ast1 but wing veins normal.

      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      ast2
      Name Synonyms
      Secondary FlyBase IDs
        References (1)