FB2026_02 , released June 18, 2026
Allele: Dmel\ast3
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General Information
Symbol
Dmel\ast3
Species
D. melanogaster
Name
FlyBase ID
FBal0000776
Feature type
allele
Associated gene
Dmel\ast
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
spontaneous
(Lewis, 1945)
Progenitor genotype
Cytology

Polytene chromosomes normal.

(Lewis, 1945)
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygotes have a similar eye phenotype to ast1, but wing venation is normal.

      (Lewis, 1945)

      S1/ast3 hatches late, has normal wing veins, and small eyes, similar to but slightly larger than S1/ast1. RK1A.

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhanced by
      Statement
      Reference

      ast3 has visible phenotype, enhanceable by E(S)1

      (Lewis, 1945)
      Other
      Statement
      Reference

      S1, ast3 has viable phenotype

      (Lewis, 1945)

      S1, ast3 has visible | dominant phenotype

      (Lewis, 1945)
      Phenotype Manifest In
      Enhanced by
      Statement
      Reference

      ast3 has eye phenotype, enhanceable by E(S)1

      (Lewis, 1945)
      Other
      Statement
      Reference

      S1, ast3 has eye phenotype

      (Lewis, 1945)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      S1 ast3 flies are late hatching, those flies which emerge have good viability and fertility, normal wing venation and extremely small eyes. The phenotype is dominantly enhanced by E(S)1; ast1 E(S)1 double heterozygotes have rough eyes.

      (Lewis, 1945)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer

      E.H. Grell, June 1965.

      Arose on: In(2L)Cy.

      Arose in: In(2L)Cy.

      (Lewis, 1945)
      Comments
      Comments

      Similar to ast1 but wing veins normal.

      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      ast3
      Name Synonyms
      Secondary FlyBase IDs
        References (2)