FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\bcd12
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General Information
Symbol
Dmel\bcd12
Species
D. melanogaster
Name
FlyBase ID
FBal0001086
Feature type
allele
Associated gene
Dmel\bcd
Associated Insertion(s)
Carried in Construct
Also Known As
bcdGB
Key Links
Genomic Maps

Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

Mutagen
ethyl methanesulfonate
(Driever and Nusslein-Volhard, 1988, Tearle and Nusslein-Volhard, 1987)
Progenitor genotype
Cytology
Description

Stop codon at amino acid position 153.

(Rivera-Pomar et al., 1996)

Amino acid replacement: Q158term.

(Struhl et al., 1989)

Nucleotide substitution: C2486T.

(Struhl et al., 1989)

The mutation is 2 amino acids downstream of the homeobox.

(Struhl et al., 1989)

2486 C --> T; 158 gln --> amber

Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
3R:6,758,201..6,758,201 [-]
Nucleotide change:

C6758201T

Reported nucleotide change:

C2486T

Amino acid change:

Q153term | bcd-PD; Q82term | bcd-PE; Q77term | bcd-PF; Q158term | bcd-PG

Reported amino acid change:

Q158term

(Struhl et al., 1989)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Strong bcd allele.

      (Driever and Nusslein-Volhard, 1988)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      References (14)