FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\bib8
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General Information
Symbol
Dmel\bib8
Species
D. melanogaster
Name
FlyBase ID
FBal0001132
Feature type
allele
Associated gene
Dmel\bib
Associated Insertion(s)
Carried in Construct
Also Known As
bibC7A
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
X ray
(Rao et al., 1990)
Progenitor genotype
Caused by aberration
In(2L)bib8
Cytology
Description

Inversion breakpoint maps within the bib transcription unit.

(Rao et al., 1990)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      bib7/bib8 embryos develop a hypertrophic nervous system at the expense of ventral cuticle. Homozygous clones in adult flies have moderately increased numbers of macrochaetae and microchaetae. These bristles have normal sockets innervated by single neurons.

      (Doherty et al., 1997)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      bib7/bib8 is rescued by bibUAS.cDa/Scer\GAL4h-1J3

      (Doherty et al., 1997)
      Comments

      These embryos are rescued by bibScer\UAS.cDa expressed under the control of Scer\GAL4h-1J3, producing embryos with nearly wild-type thoracic and abdominal cuticle without any missing denticle belts in some cases. Hypertrophy of the peripheral nervous system is also reduced in these embryos.

      (Doherty et al., 1997)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Lehmann. Campos-Ortega.

      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      bib8
      bibC7A
      (Rusconi and Corbin, 1998)
      bibC7a
      (Doherty et al., 1997, Rao et al., 1990)
      bibc7A
      (Jennings et al., 1994)
      Name Synonyms
      Secondary FlyBase IDs
        References (5)