FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
Allele: Dmel\bratts1
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General Information
Symbol
Dmel\bratts1
Species
D. melanogaster
Name
FlyBase ID
FBal0001253
Feature type
allele
Associated gene
Dmel\brat
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Wright et al., 1976)
Progenitor genotype
Cytology
Description

Amino acid replacement: G860D.

(Arama et al., 2000)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
2L:19,170,724..19,170,724 [+]
Nucleotide change:

G19170724A

Amino acid change:

G860D | brat-PA; G860D | brat-PB; G860D | brat-PC; G860D | brat-PE; G860D | brat-PF

Reported amino acid change:

G860D

Comment:

Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

(Arama et al., 2000)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
AF195872
AAF13928
 
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL
    Expression Data
    Reporter Expression
    Additional Information
    Statement
    Reference
     
    Marker for
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Disease-implicated variant(s)
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference
    External Data
    Interactions
    Show genetic interaction network for Enhancers & Suppressors
    Phenotypic Class
    Phenotype Manifest In
    Additional Comments
    Genetic Interactions
    Statement
    Reference

    Expression of either RbfHMS03004 or E2f2JF02828, under the control of Scer\GAL4nub.PU (using UAS-Dicer2 to enhance RNAi efficiency) in the bratts1 mutant background results in variable minor adult wing defects. No wing phenotype is observed upon expression of either mip130HMS00462 or mip120HMS00461 in the bratts1 mutants.

    (Miles et al., 2014)
    Xenogenetic Interactions
    Statement
    Reference
    Complementation and Rescue Data
    Comments
    Images (0)
    Mutant
    Wild-type
    Stocks (2)
    Notes on Origin
    Discoverer

    Wright.

    Comments
    Comments

    Although brat1 and brat2 fail to complement Df(2L)TW130, bratts1 is reported as complementing Df(2L)TW130.

    (Wright et al., 1976)
    External Crossreferences and Linkouts ( 3 )
    Crossreferences
    GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
    GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
    UniProt/Swiss-Prot - Manually annotated and reviewed records of protein sequence and functional information
    Synonyms and Secondary IDs (4)
    Reported As
    Symbol Synonym
    bratts1
    (Mirkovic et al., 2019, Loewen et al., 2018, Reichardt et al., 2018, Miles et al., 2014)
    l(2)37Cfts1
    l(2)E29
    (Wright et al., 1976)
    l(2)E29ts
    Name Synonyms
    Secondary FlyBase IDs
      References (7)