FB2026_02 , released June 18, 2026
Allele: Dmel\bw6
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General Information
Symbol
Dmel\bw6
Species
D. melanogaster
Name
FlyBase ID
FBal0001348
Feature type
allele
Associated gene
Dmel\bw
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
spontaneous
Progenitor genotype
Cytology
Description

Amino acid replacement: N638T. Nucleotide substitution: A1913C.

(Ewart et al., 1994)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
2R:23,528,368..23,528,368 [-]
Nucleotide change:

A23528368C

Reported nucleotide change:

A1913C

Amino acid change:

N638H | bw-PA; N638H | bw-PD

Reported amino acid change:

N638T

Comment:

The reference genomic sequence carries this mutation. The nucleotide at this location is A in wild type and C in the mutant.

(Ewart et al., 1994)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      RK1.

      (Farmer, 1974)

      Like bw1. RK1 in combination with wco2.

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Other
      Statement
      Reference

      bw6, wco2 has visible | recessive phenotype

      (Ewart et al., 1994)

      bw6, wco2 has abnormal eye color phenotype

      (Ewart et al., 1994)
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      bw6 is a suppressor of phenotype of wco2

      (Farmer, 1974)
      Other
      Statement
      Reference

      bw6, wco2 has pigment cell phenotype

      (Ewart et al., 1994)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Eye colour: brown in combination with wco2. Phenotypically silent, except in wco2 bw6 double mutant flies that contain no copies of w+ and bw+. In this case, flies have brown eyes, due to the almost complete absence of red pteridine pigments.

      (Ewart et al., 1994)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Farmer, 1974.

      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Su(wco2)+
      Su(wcoJ)+
      bw6
      Name Synonyms
      Secondary FlyBase IDs
        References (5)