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General Information
Symbol
Dmel\cact12
Species
D. melanogaster
Name
FlyBase ID
FBal0001518
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
cact011, cactO11
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Embryos show a ventralised phenotype of intermediate strength with expanded ventral epidermis and lacking dorsolaterally derived filzkorper. Injection of cactΔN25.ΔPEST or cactΔN50.ΔPEST RNA into the posterior end can rescue the ventralised phenotype. Injection of cactΔN75.ΔPEST or cactΔN83.ΔPEST causes a weak dorsal phenotype and injection of cactΔN100.ΔPEST or cactΔN125.ΔPEST causes complete dorsalisation.

Stage 2 embryos injected with cacts.2.1 transcripts exhibit rescue of filzkorper material, rescue is not observed with injection of cacta.2.1 transcripts.

Moderate ventralizing phenotype: dorsal epidermis is replaced by naked epidermis of more lateral positions and sense organs of the head are lost. Expansion of twi expression in terminal regions.

Very strong cact allele.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Suppressed by
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (4)
References (11)