Single cell class IV dendrite arborisation (da) neuron clones that are homozygous for cad² do not show defects in the establishment or maintenance of dendritic tiling.

In cad² mutant embryos, the genital disc precursor cells are disorganised and loosely packed but are wild type in number. The number of genital disc precursor cells is also not affected in cad² germline clones.

In cad² somatic clones in males, the analia (segment A10) are homeotically transformed into male genitalia (A9). In females these clones appear to become undifferentiated patches.

Examined in mosaics for effect on hindgut development. When cad activity is provided only maternally, the posterior gut appears essentially wild type. When cad is provided only zygotically, a hindgut tube is formed which can range from almost normal to reduced in length and twisted. When cad activity is completely lacking the hindgut, anal pads and eighth abdominal segment are almost entirely absent. Sections of a stage 13 embryo reveal numerous apoptotic cells in the region of the hindgut remnant. The byn-expressing ring of hindgut primordium draws together, but fails to invaginate. Germ band extension is retarded: by early stage 10 when the wild type germband is almost fully extended, the germband of cad deficient embryos is only 40% extended. The posterior midgut and Malpighian tubule primordia form and invaginate normally, though tubule elongation is incomplete.

Defects in the identity of posterior segments A9 and A10.

Nondefective in gonad assembly.