FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\ctdb3
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General Information
Symbol
Dmel\ctdb3
Species
D. melanogaster
Name
FlyBase ID
FBal0001956
Feature type
allele
Associated gene
Dmel\ct
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
diepoxybutane
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      lateral antennal lobe projection neurons (lPN) in ctdb3 homozygous somatic clones fail to target DMA, DM2 and VA5 antennal glomeruli. Mis-targeted lPN dendrites are biased towards more lateral glomeruli than in wild-type. The number of ventral antennal projection neurons (vPN) is severely reduced in these clones and those remaining mis-target their dendrites to the subesophageal ganglion. ctScer\UAS.cPa; Scer\GAL4GH146 completely rescues the Targeting of DMA, DM2 and VA5 by lPN in these animals but fails to rescue the decrease in vPN cell number and only partially rescues vPN Targeting VA1lm but not to DA1.

      (Komiyama and Luo, 2007)

      Malpighian tubules missing.

      (Blochlinger et al., 1990)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescued by

      ctdb3 is partially rescued by ctUAS.cPa/Scer\GAL4GH146

      (Komiyama and Luo, 2007)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      lethal II cut phenotypic class.

      (Blochlinger et al., 1990)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      ctdb3
      (Sugimura et al., 2004)
      cutdb3
      (Komiyama and Luo, 2007)
      Name Synonyms
      Secondary FlyBase IDs
        References (5)