FB2026_02 , released June 18, 2026
Allele: Dmel\e(faswb)1
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General Information
Symbol
Dmel\e(faswb)1
Species
D. melanogaster
Name
FlyBase ID
FBal0003305
Feature type
allele
Associated gene
e(faswb)
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
spontaneous
(Welshons and Welshons, 1986)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      By itself e(faswb) is wild type in phenotype; when in cis with Nfa-swb, either in homozygous or hemizygous condition, it produces narrow, rough, glossy eyes, bowed tibiae on the metathoracic legs and a proliferation of microchaetae. e(faswb) Nfa-swb/Nfa-g have glossy phenotype; Nfa-swb/Nfa-g have facet phenotype.

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      e(faswb)1 is an enhancer of eye phenotype of Nfa-swb

      (Welshons and Welshons, 1986)
      Other
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Enhancer of the Nfa-swb phenotype; e(faswb)1 in cis with Nfa-swb in either the homozygous or hemizygous condition produces flies with darkly pigmented, very rough, slightly narrow eyes. In addition there is a proliferation of microchaetae over the thorax, abdomen and legs, and the tibiae of the rear legs are distinctly bowed. In the absence of Nfa-swb, e(faswb)1 flies appear wild-type. e(faswb)1 rst6 flies have slightly rough eyes.

      (Welshons and Welshons, 1986)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      Comments
      Comments

      e(faswb)1 may be associated with an aberration in the region between w and N as it decreases the recombination frequency between wa and Nfa-swb. In addition it prevents recombination between wa and rst6 when heterozygous with them. It is postulated to be an inversion of bands 3C2 and 3C3 as its polytene banding pattern appears normal.

      (Welshons and Welshons, 1986)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      e(faswb)
      (Welshons and Welshons, 1986)
      e(faswb)1
      Name Synonyms
      Secondary FlyBase IDs
        References (1)