FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\E(spl)m8-HLHrv28
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General Information
Symbol
Dmel\E(spl)m8-HLHrv28
Species
D. melanogaster
Name
FlyBase ID
FBal0003349
Feature type
allele
Associated gene
Dmel\E(spl)m8-HLH
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

(Knust et al., 1987)
Mutagen
X ray
(Ziemer et al., 1988, Knust et al., 1987)
Progenitor genotype
E(spl)m8-HLH1
(Ziemer et al., 1988, Knust et al., 1987)
Caused by aberration
T(3;4)E(spl)rv6
Cytology
Description

breakpoint in m3 at -5 to -6 kb

Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygotes have weak neural hyperplasia and suppress the Nspl-1 phenotype.

      (Ziemer et al., 1988)

      Enhancement of Nspl-1 phenotypes reduced.

      (Knust et al., 1987)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Knust and Ziemer.

      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      E(spl)R-C1.4
      (Ziemer et al., 1988)
      E(spl)RC1.4
      (Knust et al., 1987)
      E(spl)rv28
      E(spl)m8-HLHrv28
      Name Synonyms
      Secondary FlyBase IDs
        References (3)