FlyBase Allele Report: Dmel\fu[39]

General Information

Symbol

Dmel\fu³⁹

Species

D. melanogaster

Name

FlyBase ID

FBal0004872

Feature type

allele

Associated gene

Dmel\fu

Associated Insertion(s)

Carried in Construct

Also Known As

fu^1PP7

Key Links

Allele class

Mutagen

ethyl methanesulfonate

Nature of the Allele

Allele class

Mutagen

ethyl methanesulfonate

(Preat et al., 1993, Eberl et al., 1992, Perrimon and Mahowald, 1987)

Progenitor genotype

Cytology

Description

Class I fu allele, affects the catalytic domain but does not change the open reading frame.

(Preat et al., 1993)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | pupal stage | recessive

(Eberl et al., 1992)

lethal | recessive | rescuable maternal effect

(Perrimon and Mahowald, 1987)

lethal | rescuable maternal effect

(Eberl et al., 1992)

Phenotype Manifest In

egg | germline clone

(Perrimon and Mahowald, 1987)

embryo | germline clone

(Perrimon and Mahowald, 1987)

embryonic abdomen | germline clone

(Perrimon and Mahowald, 1987)

embryonic thorax | germline clone

(Perrimon and Mahowald, 1987)

ovary

(Eberl et al., 1992, Perrimon and Mahowald, 1987)

Detailed Description

Statement

Reference

Germline clone analysis demonstrate maternal effect causing abnormal oogenesis.

(Eberl et al., 1992)

Abnormal oogenesis. Some of the eggs derived from homozygous germline clones arrest at early cleavage stages. Of the remaining eggs some hatch but few survive to adulthood and most of them exhibit abdominal and thoracic defects. Embryos that complete gastrulation begin to show a mild pattern of aberrant cell death but show near normal segmentation. Homozygous females are associated with a germline-dependent ovarian tumour phenotype that increases with age.

(Perrimon and Mahowald, 1987)

pupal lethal

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Suppressed by

Statement

Reference

fu³⁹ has phenotype, suppressible by Su(fu)^LP

(Preat et al., 1993)

Other

Statement

Reference

Su(fu)^LP, fu³⁹ has wing phenotype

(Preat et al., 1993)

Su(fu)^LP, fu³⁹ has leg phenotype

(Preat et al., 1993)

Su(fu)^LP, fu³⁹ has haltere phenotype

(Preat et al., 1993)

Su(fu)^LP, fu³⁹ has wing blade anterior compartment phenotype

(Preat et al., 1993)

Su(fu)^LP, fu³⁹ has leg anterior compartment phenotype

(Preat et al., 1993)

Su(fu)^LP, fu³⁹ has haltere anterior compartment phenotype

(Preat et al., 1993)

Additional Comments

Genetic Interactions

Statement

Reference

When in combination with Su(fu)^LP heterozygotes individuals display a partially suppressed fu phenotype.

(Preat et al., 1993)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Perrimon.

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

fu^1PP7

(Preat et al., 1993, Eberl et al., 1992, Perrimon and Mahowald, 1987)

fu³⁹

fu^IPP2

(van den Heuvel et al., 1993)

fu^IPP7

Name Synonyms

Secondary FlyBase IDs

FBal0034711

References (4)

Report Sections

Open Close