FB2026_02 , released June 18, 2026
Allele: Dmel\inaC1
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General Information
Symbol
Dmel\inaC1
Species
D. melanogaster
Name
FlyBase ID
FBal0005599
Feature type
allele
Associated gene
Dmel\inaC
Associated Insertion(s)
Carried in Construct
Also Known As
inaC207
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
Progenitor genotype
Cytology
Description

Point mutation resulting in an amino acid replacement.

(Matsumoto et al., 1994)

Nucleotide substitution: T602A. Amino acid replacement: V201D.

(Smith et al., 1991)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
2R:16,899,521..16,899,521 [+]
Nucleotide change:

T16899521A

Amino acid change:

V201D | inaC-PA

(Smith et al., 1991)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Photoreceptors of homozygotes are unable to carry out normal rapid deactivation after a light stimulus, due to a defect in the calcium-dependent deactivation mechanism. Excitation mechanisms appear to be unaffected.

      (Ranganathan et al., 1991)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer

      Pak.

      Comments
      Comments

      Retinal homogenate is capable of phosphorylating endogenous Arr2 in vitro.

      (Matsumoto et al., 1994)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      P207
      inaC1
      inaC207
      (Ranganathan et al., 1991, Smith et al., 1991)
      inaCP207
      (Matsumoto et al., 1994)
      Name Synonyms
      Secondary FlyBase IDs
        References (3)