FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
Allele: Dmel\L5
Open Close
General Information
Symbol
Dmel\L5
Species
D. melanogaster
Name
FlyBase ID
FBal0005885
Feature type
allele
Associated gene
Dmel\L
Associated Insertion(s)
hopper{}L5
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Associated Insertion(s)
    hopper{}L5
    Cytology
    Description

    1.4kb hopper insertion in the first intron of the L-RC isoform. In addition, the chromosome also carries a number of other natural transposon insertions in the L region (jockey{}Mohr, opus{}Mohr and roo{}Mohr), however these insertions are found in a number of dominant L mutant alleles isolated around 1920, and also in the ft1 chromosome isolated during the same time period, suggesting that the additional insertions are probably not related to the dominant L mutant eye phenotype.

    (Son and Choi, 2020)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Heterozygotes have a nick near the anterior midline of the eye and the overall size of the eye is reduced.

        (Chern and Choi, 2002)

        Heterozygote has small nick in eyes; overlaps wild type. Homozygote has small eyes and tendency to antenna reduplicaion. May be used as a recessive but not as a dominant.

        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Suppressed by
        Statement
        Reference

        L5 has visible | dominant | adult stage phenotype, suppressible by hyxEY06898

        (Zhang et al., 2010)
        Phenotype Manifest In
        Suppressed by
        Statement
        Reference

        L5 has eye phenotype, suppressible by hyxEY06898

        (Zhang et al., 2010)
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Rescued by

        L5/L[+] is rescued by LGLV21080/Scer\GAL4ey.PU

        (Son and Choi, 2020)
        Comments

        Expression of LGLV21080 under the control of Scer\GAL4ey.PU strongly suppresses the L5/+ eye phenotype.

        (Son and Choi, 2020)
        Images (0)
        Mutant
        Wild-type
        Stocks (1)
        Notes on Origin
        Discoverer

        Mohr, 26th Nov. 1931.

        Comments
        Comments

        Phenotypic series: L1 > L5 > Lr.

        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        L5
        (Son and Choi, 2020, Zhang et al., 2010, Bischoff et al., 2009)
        Name Synonyms
        Secondary FlyBase IDs
          References (8)