FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\br2Bd
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General Information
Symbol
Dmel\br2Bd
Species
D. melanogaster
Name
FlyBase ID
FBal0006662
Feature type
allele
Associated gene
Dmel\br
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

hypomorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

hypomorphic allele - genetic evidence

(Gonzy-Treboul et al., 1995, Restifo and Merrill, 1994, Demakova et al., 1988)
Mutagen
ethyl methanesulfonate
(Restifo and Merrill, 1994, Kiss et al., 1988, Belyaeva et al., 1982)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      At all temperatures 1--40% br2Bd/T(1;2)dorvar7 females have 1-2 bristles on maxillary palps missing or reduced.

      (Demakova et al., 1988)

      Deficient in 'rbp' function.

      (Kiss et al., 1988)

      Rare survivors heterozygotes and heterozygotes with Df(1)RA19 exhibit faded wings, swollen abdomen and reduced bristle number on the palpus. Most individuals die at the late pupal stage.

      (Belyaeva et al., 1982)

      Males and homozygous females display normal phenotype and viability; however, in heterozygous combination with deficiencies or 'npr' mutations, temperature-sensitive lethal; completely lethal at 29oC; at 25oC or 18oC most individuals die in late pupal stage and survivors have faded wings, swollen abdomen and reduced bristle number on palpi.

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      No change in late gene expression in br2Bd individuals.

      (Guay and Guild, 1991)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (6)
      Reported As
      Symbol Synonym
      br2Bd
      l(1)2Bd1
      l(1)pp-2
      l(1)pp-2t252
      (Belyaeva et al., 1980)
      l(1)t252
      (Demakova et al., 1988)
      t252
      (Belyaeva et al., 1982)
      Name Synonyms
      Secondary FlyBase IDs
        References (9)