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General Information
Symbol
Dmel\Hr3802306
Species
D. melanogaster
Name
FlyBase ID
FBal0007996
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
l(2)02306
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

P{PZ} insertion 34bp upstream of the start of the Hr38 cTK61 isoform.

P{PZ} insertion 8bp downstream of a potential TATA box for Hr38 and 17 bp upstream of a TCAGT motif commonly associated with transcription start sites.

Insertion components
P{PZ}Hr3802306
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Homozygotes show local fragility of the adult cuticle; the cuticle in the leg joints is ruptured by mechanical stress, leading to melanisation of the damaged spots. The flies subsequently die as pharate adults or within a few hours after eclosion.

Eclosing adults appear initially normal but die within a few hours following rupture of the cuticle at joints. Ruptures become melanized.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer

A. Spradling.

Comments
Comments

Excision of the P{PZ} is accompanied by reversion of the mutant phenotype.

Complements: diak07135. Complements: diak07140. Complements: l(2)01528k13715a. Complements: dppk17036a. Complements: dia1.

External Crossreferences and Linkouts ( 1 )
Crossreferences
GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
Synonyms and Secondary IDs (3)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (11)