FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\l(2)glD150
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General Information
Symbol
Dmel\l(2)glD150
Species
D. melanogaster
Name
FlyBase ID
FBal0009245
Feature type
allele
Associated gene
Dmel\l(2)gl
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
spontaneous
natural population
(Mechler et al., 1985)
Progenitor genotype
Cytology
Description

Deletion of sequences from 0 to 17kb (coordinates with respect to proximal end of a cloned l(2)gl region, close to the tip of 2L).

(Mechler et al., 1985)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      l(2)glD150/l(2)gl119 transheterozygotes show temperature-sensitive viability. The temperature-sensitive period is in the third larval stage.

      (Sokolova and Golubovsky, 1979)

      Some l(2)glD150/l(2)gl119 flies are viable. The viability is affected by temperature; the temperature sensitive period is during the third larval stage.

      (Sokolova and Golubovsky, 1978)

      97.3% of mutants die as larvae, 2.7% as pupae. Extreme allele: larval brain and optic lobes become enlarged and disorganised and the imaginal discs are large and clumped. Discs of mutant larvae transplanted into wild-type female abdomens form large contained tumours, whereas transplanted optic primordia from larval brains form invasive neuroblastomas, which grow rapidly, killing the host within 7-14 days. These tumours can be serially cultured in adult abdomens.

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Isolated from: Dilizhan, Armenia, USSR population.

      (Mechler et al., 1985)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      D150
      (Sokolova and Golubovsky, 1979, Gateff, 1978)
      l(2)glD150
      Name Synonyms
      Secondary FlyBase IDs
        References (5)