FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\l(2)me1
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General Information
Symbol
Dmel\l(2)me1
Species
D. melanogaster
Name
FlyBase ID
FBal0009285
Feature type
allele
Associated gene
l(2)me
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
spontaneous
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous larvae stop growing at the second instar stage and die after 7-8 days.

      (Kubli, 1978)

      Larvae do not grow normally and die while small. Body length remains relatively shorter than tracheal stems, which become convoluted in a meandering manner. Salivary glands reach 30% normal size. Pharyngeal development is normal. RK3.

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Intestines lack proteolytic enzymes.

      The isoacceptor pattern of tRNA:E4 is altered in l(2)me1 mutant flies, supporting the hypothesis that the l(2)me1 mutation may be a deletion of part of the tRNA:E4 cistrons (and Hex-C) located at 2-72.

      (Kubli, 1978)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      l(2)me
      (Kubli, 1978)
      l(2)me1
      Name Synonyms
      Secondary FlyBase IDs
        References (1)