FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\l(3)s1754s1754
Open Close
General Information
Symbol
Dmel\l(3)s1754s1754
Species
D. melanogaster
Name
FlyBase ID
FBal0011135
Feature type
allele
Associated gene
l(3)s1754
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
Progenitor genotype
Cytology
Description

The mutation may be caused by an insertion, as the lethality can be reverted by Delta2-3 mediated excision.

(Hain and Müller, 2013.8.16)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      M. Scott.

      Separable from: P{lacW}CG7427s1754.

      (Hain and Müller, 2013.8.16)

      The lethality of the "l(3)s1754" chromosome (represented by l(3)s1754s1754) is separable from the P{lacW}CG7427s1754 insertion in the CG7427 gene: the lethality of the chromosome is complemented by a deficiency (Df(3L)XG9) which uncovers the CG7427 gene. In addition, the lethality of the chromosome can be reverted to viability by Delta2-3 mediated excision, suggesting that the lethal allele (l(3)s1754s1754) is potentially also associated with an insertion and thus that there may be two insertions on the third chromosome in this line.

      (Hain and Müller, 2013.8.16)
      Comments
      Comments

      Complements: CrebA03576. Complements: cpo03603.

      (BDGP Project Members, 1994-1999)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      l(3)s1754
      (Spradling et al., 1999)
      l(3)s1754s1754
      (Mishra et al., 2020)
      Name Synonyms
      Secondary FlyBase IDs
        References (6)