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General Information
Symbol
Dmel\lab4
Species
D. melanogaster
Name
FlyBase ID
FBal0011517
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
labf8
Key Links
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology

Polytene chromosomes normal.

Nature of the lesion
Statement
Reference
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

In lab4 mutant clones in the anterior head, vibrissae are disrupted or missing, the ventral edge of the eye is deleted, and maxillary palps are missing. In posterior head clones, novel bristles appear in the postgena.

The average number of crystal cells per embryo is reduced in homozygous stage 13-14 embryos compared to wild type.

No salivary gland defects.

No change in the spatial distribution of ae mRNA.

Hemizygous animals die at the embryonic/first larval instar border. A variable cuticle phenotype is seen, with the severity of the defects correlating with the degree of failure of head involution. The frontal sac appears collapsed, and the pharynx occupies a more anterior position than normal. The salivary glands are missing. Homozygous mutant clones in the head have a mutant phenotype - novel tissue is seen in the postgena and other structures are disrupted.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (2)
Notes on Origin
Discoverer

Fornili.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
References (11)