FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\lab15
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General Information
Symbol
Dmel\lab15
Species
D. melanogaster
Name
FlyBase ID
FBal0011528
Feature type
allele
Associated gene
Dmel\lab
Associated Insertion(s)
Carried in Construct
Also Known As
labvd2
Key Links
Genomic Maps

Allele class

hypomorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

hypomorphic allele - genetic evidence

(Chouinard and Kaufman, 1991, Merrill et al., 1989)
Mutagen
X ray
(Merrill et al., 1989)
Progenitor genotype
Cytology

Polytene chromosomes normal.

(Diederich et al., 1989, Merrill et al., 1989)
Description

Insertion of about 600bp.

(Diederich et al., 1989)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
insertion
3R:6,677,586..6,678,199 [-]
Linked to:
PstI-BamHI restriction fragment
Comment:

Approximate position of insertion_site inferred by curator from Figure 1 of FBrf0049820.

(Diederich et al., 1989)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Hemizygous animals die at the embryonic/first larval instar border. A variable cuticle phenotype is seen, with the severity of the defects correlating with the degree of failure of head involution. The frontal sac appears collapsed, and the pharynx occupies a more anterior position than normal. The salivary glands are missing.

      (Merrill et al., 1989)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Diederich.

      R. Diederich.

      (Merrill et al., 1989)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      VD-2
      (Kaufman et al., 1990)
      lab15
      labvd2
      (Diederich et al., 1989, Merrill et al., 1989)
      Name Synonyms
      Secondary FlyBase IDs
        References (4)