FB2026_02 , released June 18, 2026
Allele: Dmel\Abd-BMc
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General Information
Symbol
Dmel\Abd-BMc
Species
D. melanogaster
Name
Microcephalus
FlyBase ID
FBal0012109
Feature type
allele
Associated gene
Dmel\Abd-B
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
spontaneous
Progenitor genotype
Caused by aberration
Dp(3;3)Mc
Cytology
Description

A 9kb EcoRI fragment that covers the iab-7 region is unique to Abd-BMc. Associated with a partial duplication of the Abd-B domain.

(Hopmann et al., 1995)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Displays locomotor activity rhythm with an approximately 24h period.

      (Vosshall and Young, 1995)

      Eyes of heterozygote small or absent. Scutellar bristles curve upward. Homozygote usually more extreme than heterozygote but not reliably distinguishable. Viability of homozygote varies from 100% down to 40%. ale1 Abd-BMc homozygotes completely eyeless; fertile except when crossed to each other (FBrf0023540). RK1A

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Ubxbx-34e Abd-BMc double heterozygous females show a significant increase in the level of monoene cuticular hydrocarbons and a significant decrease in the level of 7,11-diene cuticular hydrocarbons compared to wild-type females.

      (Wicker-Thomas and Jallon, 2001)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      Abd-BMc
      Mc
      (Vosshall and Young, 1995)
      Mc1
      Name Synonyms
      Microcephalus
      (Duncan and Montgomery, 2002, Hopmann et al., 1995)
      Secondary FlyBase IDs
        References (11)