FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\msl-2kmA
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General Information
Symbol
Dmel\msl-2kmA
Species
D. melanogaster
Name
FlyBase ID
FBal0012563
Feature type
allele
Associated gene
Dmel\msl-2
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Pierre, 1972)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous males die during an early stage of embryogenesis.

      (Pierre, 1972)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to complement

      msl-2227

      (Bevan et al., 1993)
      Comments

      msl-2kmA/msl-2227 males do not survive, dying as larvae.

      (Bevan et al., 1993)
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer
      Comments
      Comments

      The "early" embryonic lethality of males homozygous for the msl-2kmA chromosome (reported in FBrf0063797) may be due to mutations at other loci, as msl-2kmA/msl-2227 males die as larvae.

      (Bevan et al., 1993)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (5)
      Reported As
      Symbol Synonym
      km(2)A
      (Pierre, 1972)
      kmA
      (Bevan et al., 1993)
      msl-2kmA
      (Valsecchi et al., 2021, Valsecchi et al., 2018)
      msl2kmA
      (McCarthy et al., 2022)
      Name Synonyms
      killer of males
      Secondary FlyBase IDs
        References (5)