FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\opht1
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General Information
Symbol
Dmel\opht1
Species
D. melanogaster
Name
FlyBase ID
FBal0013276
Feature type
allele
Associated gene
opht
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
spontaneous
(Postlethwait, 1974)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      opht1 is an enhancer of visible | cold sensitive phenotype of Dfdr

      (Postlethwait, 1974)

      opht1 is an enhancer of visible | cold sensitive phenotype of ld1

      (Postlethwait, 1974)
      Other
      Statement
      Reference

      ld1, opht1 has visible | homeotic phenotype

      (Ouweneel, 1970)
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      opht1 is an enhancer of eye | cold sensitive phenotype of Dfdr

      (Postlethwait, 1974)

      opht1 is an enhancer of eye | cold sensitive phenotype of ld1

      (Postlethwait, 1974)
      Other
      Statement
      Reference

      ld1, opht1 has eye phenotype

      (Ouweneel, 1970)

      ld1, opht1 has wing | ectopic phenotype

      (Ouweneel, 1970)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      A semidominant enhancer of ld1 and Dfdr and perhaps other eye-shape mutants. In the presence of opht, flies bearing the above mutants produce wing-like outgrowths in the eye. Expression more extreme at 17oC than at 29oC; temperature-sensitive period in second and third instar larvae.

      (Postlethwait, 1974)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      opht1
      Name Synonyms
      Secondary FlyBase IDs
        References (2)