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General Information
Symbol
Dmel\osk5
Species
D. melanogaster
Name
FlyBase ID
FBal0013307
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
osk150
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Nucleotide change:

G8937324A

Reported nucleotide change:

C2507A

Amino acid change:

R593Q | osk-PA; R455Q | osk-PC; R241Q | osk-PD

Reported amino acid change:

R593Q

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Amino acid replacement: R593Q. Nucleotide substitution: G2507A.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Stage 10b oocytes in osk1/osk5 females do not have long F-actin projections in the posterior region, in contrast to wild type.

Maternal effect phenotype when in trans with a deficiency for osk.

Lack posterior body pattern elements and germ cells.

Absence of posterior pole plasm, polar granules and pole cells.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
Comments
Comments

Normal localization of osk mRNA.

Strong allele of osk. The abdominal phenotype of osk can be rescued by cytoplasmic transplantation of wild type posterior pole plasm into the abdominal regions of mutant embryos.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
References (13)