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Citation
Kim-Ha, J., Smith, J.L., MacDonald, P.M. (1991). oskar mRNA is localized to the posterior pole of the Drosophila oocyte.  Cell 66(1): 23--35.
FlyBase ID
FBrf0053359
Publication Type
Research paper
Abstract

Mutants of the maternal posterior-group genes of Drosophila lack posterior body pattern elements and germ cells, both of which form through the action of determinants localized to the posterior pole of the oocyte. We report that transcripts of one of these genes, oskar, become localized to the posterior pole of oocytes shortly after the oocyte begins to differentiate visibly. Analysis of various posterior-group mutants reveals that localization of oskar mRNA is an early step in the posterior localization pathway. In addition, we find that nonsense oskar mutations disrupt osk mRNA localization, while missense oskar mutations do not.

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    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Cell
    Title
    Cell
    Publication Year
    1974-
    ISBN/ISSN
    0092-8674
    Data From Reference
    Aberrations (3)
    Alleles (23)
    Genes (9)
    Molecular Constructs (1)
    Insertions (1)
    Transgenic Constructs (1)