FlyBase Allele Report: Dmel\osk[unspecified]

General Information

Symbol

Dmel\osk^unspecified

Species

D. melanogaster

Name

FlyBase ID

FBal0065720

Feature type

allele

Associated gene

Dmel\osk

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Cytology

Description

FlyBase curator comment: this entry is used to capture phenotypic information when the particular allele (or allele combination) used by the author could not be determined but the context of the experiment suggests that the phenotype being described is some kind of loss of function.

(FlyBase Curators, 2025-)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

embryonic abdominal segment 1

(Tearle and Nusslein-Volhard, 1987)

embryonic abdominal segment 2

(Tearle and Nusslein-Volhard, 1987)

embryonic abdominal segment 3

(Tearle and Nusslein-Volhard, 1987)

embryonic abdominal segment 4

(Tearle and Nusslein-Volhard, 1987)

embryonic abdominal segment 5

(Tearle and Nusslein-Volhard, 1987)

embryonic abdominal segment 6

(Tearle and Nusslein-Volhard, 1987)

embryonic abdominal segment 7

(Tearle and Nusslein-Volhard, 1987)

embryonic abdominal segment 8

(Tearle and Nusslein-Volhard, 1987)

embryonic abdominal segment 9

(Tearle and Nusslein-Volhard, 1987)

embryonic abdominal segment 10

(Tearle and Nusslein-Volhard, 1987)

embryonic abdominal segment 11

(Tearle and Nusslein-Volhard, 1987)

gamma-tubulin complex | oogenesis

(Kenny et al., 2021)

gamma-tubulin complex | oogenesis, with osk^{3'977-981.Tag:HA}

(Kenny et al., 2021)

gamma-tubulin complex | oogenesis, with osk^{3'1001-1015.Tag:HA}

(Kenny et al., 2021)

gamma-tubulin complex | oogenesis, with osk^{3'BRE-II.Tag:HA}

(Kenny et al., 2021)

germinal proliferation center hub

(Voog et al., 2008)

microtubule | oogenesis

(Kenny et al., 2021)

microtubule | oogenesis, with osk^{3'977-981.Tag:HA}

(Kenny et al., 2021)

microtubule | oogenesis, with osk^{3'1001-1015.Tag:HA}

(Kenny et al., 2021)

microtubule | oogenesis, with osk^{3'BRE-II.Tag:HA}

(Kenny et al., 2021)

oocyte

(Kenny et al., 2021)

oocyte, with osk^{3'977-981.Tag:HA}

(Kenny et al., 2021)

oocyte, with osk^{3'1001-1015.Tag:HA}

(Kenny et al., 2021)

oocyte, with osk^{3'BRE-II.Tag:HA}

(Kenny et al., 2021)

pole plasm

(Tearle and Nusslein-Volhard, 1987)

primordial germ cell

(Tearle and Nusslein-Volhard, 1987)

Detailed Description

Statement

Reference

osk^unspecified mutant testes exhibit an apparent expansion of the apical hub.

(Voog et al., 2008)

Embryos derived from osk^unspecified mutant females lack pole cells, pole plasm and abdominal segments.

(Tearle and Nusslein-Volhard, 1987)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Suppressed by

Statement

Reference

osk^unspecified has germinal proliferation center hub phenotype, suppressible by esg^shof

(Voog et al., 2008)

osk^unspecified has abdominal segment phenotype, suppressible by nanos^SRE1.SRE2

(Smibert et al., 1996)

NOT suppressed by

Statement

Reference

osk^unspecified has abdominal segment phenotype, non-suppressible by nanos^+mSa

(Smibert et al., 1996)

Additional Comments

Genetic Interactions

Statement

Reference

The apical hub phenotype in osk^unspecified mutant testes is suppressed by esg^shof-homozygosity.

(Voog et al., 2008)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

osk^unspecified is rescued by osk^{3'Δ370-390.Tag:HA}

(Kenny et al., 2021)

osk^unspecified is rescued by osk^+t4.3

(Kim-Ha et al., 1991)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

osk^unspecified

Name Synonyms

Secondary FlyBase IDs

References (10)

Report Sections